Experimental ‘Pill’ for Males on Distant Horizon

Holy Hormones Journal:
Funny – the ‘experimental pill for women was rushed through the FDA and onto the market even though women in Puerto Rico who were the r-CONFUSED-MAN-WITH-PILL-large570first medical experiments – said ‘no way’ – and even though there was a Senate testimony meeting in 1970 where a medical expert stated:

Estrogen is to cancer
like fertilizer is to wheat.”

And still the pill is on the market.

Yet we have heard about this ‘male pill’ for decades and it is still in the lab.  Personally, I think they cannot come up with a good marketing campaign to sell it to men. I think the picture on the right says it all. Men aren’t dumb – are they really going to take a hormone pill that they see their partners struggle with? Besides they gotta protect them sperm and their manhood. Sterilization with a pill is just not going to cut it.

On the other hand it appears that the HPV vaccine Gardasil now marketed to for boys – is doing what the male pill can’t do. The best part is the boys are not aware – and that is the optimum design for a medical experiment.

More on this later.

Why some experimental forms of ‘The Pill for Males’ will never rise to the occasion

ScienceDaily

Date:
June 2, 2014
Source:
Federation of American Societies for Experimental Biology
Summary:
It appears that ‘The Pill’ for men will have to wait a while longer. A new research study involving mice shows that a previously developed male hormonal oral contraceptive method (i.e. via testosterone) is unable to stop the production and/or release of sperm. Scientists demonstrated that the male contraception approach by testosterone has an inherent problem — spermatogenesis does not stop. They found that that administering increasing doses of testosterone to infertile mutant mice did allow sexual function to return at a certain dosing threshold, however spermatogenesis also returned at that dose.

It appears that “The Pill” for men will have to wait a while longer. A new research report published in the June 2014 issue of The FASEB Journal involving mice, shows that a previously developed male hormonal oral contraceptive method (i.e. via testosterone) is unable to stop the production and / or the release of sperm.

“Our research in mice explains why the efficacy of male hormonal contraception is not as effective as expected and it provides clues on how to improve the method,” said Ilpo Huhtaniemi, M.D., Ph.D., M.D.hc, FMed.Sci., a researcher involved in the work from the Institute of Reproductive and Developmental Biology at the Imperial College of London in London, UK.

Scientists demonstrated in experimental mice that the male contraception approach by testosterone has an inherent problem — spermatogenesis does not stop. They found that that administering increasing doses of testosterone to infertile mutant mice did allow sexual function to return at a certain dosing threshold, which was expected. What was not expected, however, is that spermatogenesis also returned at that dose. This suggests that it is impossible to give a single dose of testosterone that allows for sexual function and the suppression of pituitary gonadotropin secretion, but also does not initiate sperm production.

Ever since The Pill was developed, we’ve been aiming for an equivalent for men,” said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. “This report suggests that we may be finally reaching the end of administering testosterone for this purpose.”

Read full article…

PG

Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.