Thursday’s interview with Chandler Marrs,PhD and Susan Rex Ryan is now posted. I am grateful to both of these women for sharing their information and knowledge about molecular mimicry and autoimmunity.
Chandler Marrs PhD, Susan Rex Ryan and Leslie Carol Botha
“Molecular Mimicry –
A Trojan Horse or A False Flag?”
Holy Hormones Honey!
VoiceAmerica Health and Wellness Channel
Noon ET – 9 am PT
Why is it that some people are able to defend a viral attack and others are not? Why is it that some children develop autism, or suffer a severe reaction to a vaccine – while others do not? And why do some people react to certain medications – while others have no reaction at all?
According to some researchers’ molecular mimics or snippets of protein code from foreign pathogens like bacteria, viruses and vaccines that are similar enough in structure or function to the body’s innate, ‘self’ peptide sequences become a Trojan horse tricking the body into activating or over-activating an immune response. Molecular mimicry has been implicated in vaccine adverse reactions and in the onset of Type 1 Diabetes, Lupus, MS, neurological and other chronic diseases.
Some researchers argue that molecular mimicry abounds and other factors exist to predispose one to disease or adverse reactions. Which is it? What are those ‘other factors’?
And why is it that some are able to fend off the Trojan attack while others suffer immeasurably? Pharmaceutical companies have used this conundrum to their advantage in dening ‘causal’ links between the drug and the reaction effectively negating liability.
Marrs, Ryan and Botha will discuss the interaction between molecular mimicry, healthy immune functioning and vaccine/drug adverse reactions. They will provide explanations and simple steps to increase immune functioning.
The topic for this show came up during a collaborative discussion between Chandler Marrs, who just posted an informative article on Molecular Mimicry on her blog, Hormones Matter. The article entitled: ‘Molecular Mimicry and Autoimmune Disease‘ caught my attention immediately as Marrs defined molecular mimics.
Molecular mimics are snippets of protein code embedded within the pathogen that are either functionally similar and contain sequences of identical code to those found innately in humans, or structurally similar and because of their shape can bind to and activate an immune cell receptor. The protein codes, called motifs, are instructions that govern all aspects of the cell’s activity levels, and indeed, our very health and survival. Some codes tell the cell to live and how to function, others tell the cell to die and even how to die.
Marrs goes on to write about the HPV vaccines and the autoimmune diseases that have affected so many girls and women:
Similarly, molecular mimicry has been suspected in the autoimmune diseases that emerge post Gardasil or Cervarix, the HPV vaccines. With the HPV vaccines, researchers have identified 82 pentamer (5) level mimics and 34 heptamer (7) level mimics in the HPV 16L component. The offending motifs control a variety of cell behaviors related to cardiac functioning, cell permeability and cell death. This finding led the researcher to postulate that the mimicked motifs controlling cardiac functioning could be culprits in the post HPV vaccine incidences of sudden death.
Sue Rex Ryan joined in the conversation, mentioning the article she wrote on adaptive immunity and Vitamin D3 – also posted on the Hormones Matter blog, in September 2013. Her article, entitled: ‘Vitamin D Plays an Integral Role in Adaptive Immunity’ made me begin to wonder if the fault was entirely on the dangerous vaccines and medications on the market – or if there some personal culpability involved in our lack of knowledge about the crucial role nutrition (micronutrients) plays – education that extends far beyond the government’s ‘Choose My Plate’ campaign.
Sue’s compelling article points out what happens to an adaptive immune system gone awry. And as a proponent of Vitamin D3 therapy, she points out that the lack of this essential hormone may be factored in as to why the influence of molecular mimickers may be misconstrued by the body.
Vitamin D Helps Regulate the Adaptive Immune System
The adaptive immune system comprises the body’s intricate network of antibodies and special types of white blood cells (called sensitized lymphocytes ) to thwart new and previous invaders including viruses, bacteria, and drugs. When the adaptive immune system is not strong enough to endure external disruptions such as severe side effects of drugs, it can go awry by signaling antibodies and sensitized lymphocytes to attack healthy cells. This response is called autoimmunity—when the adaptive immune system’s cells do not recognize previous invaders and designate healthy cells as those invaders. In other words, the body’s immune cells attack its own healthy cells.
Scientific research over the past three decades solidifies the connection between vitamin D and autoimmunity. Vitamin D plays an integral role in the regulation of the adaptive immune system. Adequate vitamin D in our bodies can protect us from autoimmunity because adaptive immune cells contain vitamin D receptors (VDRs). These receptors are attached to the surface of the adaptive immune system’s antibodies and sensitized lymphocytes. The VDRs act as “gate keepers” by signaling what external substances, e.g., components of medications, can enter a cell. The VDRs must be replete with vitamin D to effectively regulate adaptive immunity. When the VDRs receive adequate amounts of vitamin D, they enable the adaptive immune system to function properly by attacking new and previous invaders.
Leslie Carol Botha, will examine the role of fluctuating hormones and the lack of understanding about the phases of the menstrual cycle and how that may lead to autoimmunity. Botha has written many times about the importance of vaccination, introduction of medications and the scheduling of surgeries around the times of the menstrual cycle when women’s immunity is at it highest. She has been vocal about vaccinating girls during menarche – when they are most fragile. And she also believes that vaccination without regard to where a woman is in her menstrual cycle may also be another factor for causing damage to the neurological, endocrine and immune systems. Botha believes that hormone health is crucial to women’s health and well-being. Damaged and or mixed messages sent by hormones to receptors can damage cell health.
Chandler, Marrs PhD, founder of Hormones Matter and Lucine Biotechnology Ltd, Susan Rex Ryan, author of the award-winning vitamin D book, Defend Your Life , and Leslie Carol Botha, co-author of Understanding Your Mind, Mood and Hormone Cycle share their insights, research and knowledge on how vaccines and drugs may be the Trojan horse affecting the mitochondrial health of the cells in our bodies.
Self-proclaimed biology watcher, Lewis Thomas in his award-winning book, The Lives of a Cell, states most eloquently, that somehow we have gotten the concept of disease and death all wrong. He states that viruses and pathogens in the body were designed to live in symbiotic harmony and that it would take many years before they develop an antagonistic predatory relationship. What has happened? Are our bodies the new Armageddon?
Definitions of terms used during the show:
Molecular Mimicry: Defined as the theoretical possibility that sequence similarities between foreign and self-peptides are sufficient to result in the cross-activation of autoreactive T or B cells by pathogen-derived peptides. ~ Wikipedia
Self vs. Non Self Immune System Theory: The key to a healthy immune system is its remarkable ability to distinguish between the body’s own cells, recognized as “self,” and foreign cells, or “nonself.” The body’s immune defenses normally coexist peacefully with cells that carry distinctive “self” marker molecules. But when immune defenders encounter foreign cells or organisms carrying markers that say “nonself,” they quickly launch an attack. ~NIAID
Damage Immune System Theory: The damage or error theory include 1) Wear and tear theory. Cells and tissues have vital parts that wear out resulting in aging. Like components of an aging car, parts of the body eventually wear out from repeated use, killing them and then the body. So the wear and tear theory of aging was first introduced by Dr. August Weismann, a German biologist, in 1882, it sounds perfectly reasonable to many people even today, because this is what happens to most familiar things around them. ~ Modern Biological Theories of Aging, NCBI