Hormones and Psychosis

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Holy Hormones Journal: Psychosis – how many people do you know who are struggling with some form of this label? Not to mention the stigma that goes along with this diagnosis.

Could psychosis, after all be related to hormones, adrenal fatigue and stress? Is psychosis due to hormone imbalance? Do we really need the drugs for treatment or do we need to be learning how to live with the cycles of life? Our hormones rise, our hormones fall – this is true for women and men as it is true for all of nature. Circadian rhythms. We are just beginning to understand the importance of these rhythms in our lives. I for one, have known about them for years…. because I have observed the changes in women’s mind, mood, and behavior as their hormones shift.  My co-author Sandi Batik and I wrote about this beautiful cycle in our book, “Understanding Your Mind, Mood, and Hormone Cycle.”

The deal is – the body does not recognize good stress from bad stress. And most of us lead a stressed life and do not recognize the importance of slowing down.

“It’s almost as if being stressed makes us feel important, valuable, and useful. But the biggest problem with being a stress addict is that it can destroy our health.” Source

“There is a time to give and a time to receive…” this tidbit of biblical knowledge is the source of life in our universe. Every cell in our body – every life form on our planet responds to they cycle of waxing and waning.  When we live outside the cycle, our body breaks down and we develop a variety of pathological and physiological diseases based on our biochemical makeup. Now it appears that psychosis may be one of them. Think of the extremely high functioning, creative people in your life. People who are obsessed with their work and their mission. People who work around the clock. And then one day – it seems they have taken a left turn to nowhere – which may includ addiction – but may also included passive aggressive, sociopathic, obsessive compulsive behaviors. People who rant and talk about themselves all of the time. Hormone-induced psychosis.

ScienceDaily also published a study from Texas A & M University on June 1 citing that: Shift work unwinds body clocks, leading to more severe strokes -Research finds living against our body clocks is detrimental to our health.

Statistics show that some 15 million Americans don’t work the typical nine-to-five. These employees (or shift workers), who punch in for graveyard or rotating shifts, are more prone to numerous health hazards, from heart attacks to obesity, and now, new research shows shift work may also have serious implications for the brain. Source

Cycles – in particular the menstrual cycle, are crucial to our health and well being. To suppress/ignore cycles… to put it aptly… is killing us. 

Stress hormone link with psychosis


Date:June 3, 2016
Source:James Cook University
Summary:A link between levels of the stress hormone cortisol and psychosis has been discovered by researchers, which could help identify people at greatest risk of developing the severe mental disorder.


JCU Associate Professor Zoltan Sarnyai said it was the first meta-analysis study to compare the level of cortisol in a waking patient’s body with the stage of schizophrenia they are suffering.

Dr Sarnyai said it means doctors may be able to eventually identify those who will develop full-blown psychosis from amongst those who present with early stages of the disease.

“Only some 20 to 30 per cent of individuals who are at high-risk of developing psychosis due to their clinical presentation or family history actually do so. Identifying those people early is where the cortisol measurement comes in.

“Biomarkers are very few and far between in psychiatry, so even though a huge amount of work is still needed, this could become a valuable technique,” said Dr Sarnyai.

Researchers at the Psychiatric Neuroscience Laboratory at the Australian Institute of Tropical Health and Medicine (AITHM) at JCU, conducted a meta-analysis of 11 studies.

The resulting paper, published in Neuroscience & Biobehavioral Reviews, shows that patients have different levels of the stress hormone after awakening (Cortisol Awakening Response, CAR) relative to healthy controls.

Co-author of the study, JCU’s Dr Maximus Berger, said scientists had suspected cortisol had a role in psychotic disorders for a long time, but until now, some results had been contradictory.

“We were able to show that patients with psychosis fail to produce cortisol after they wake up in the morning. We found this even in patients with recent onset of the illness,” said Dr Berger.

The paper identified some evidence to suggest that high-risk individuals who later develop psychosis already have changes in cortisol before they develop the illness.

Dr Sarnyai said low CAR levels are also an indicator of risk for other chronic diseases and have been linked to systemic inflammation and changes in the gut flora — which meant there was the potential for early diagnosis and treatment of these conditions too.

Story Source:

The above post is reprinted from materials provided by James Cook University. Note: Materials may be edited for content and length.

Journal Reference:

  1. Maximus Berger, Ann Katrin Kraeuter, Daria Romanik, Peter Malouf, G. Paul Amminger, Zoltán Sarnyai. Cortisol Awakening Response in Patients with Psychosis: Systematic Review and Meta-Analysis. Neuroscience & Biobehavioral Reviews, 2016; DOI: 10.1016/j.neubiorev.2016.05.027



I am including the HorMoon Awareness Guide that I created to help you understand that phases that you go through every month of your life. We are maidens, mothers’ and wise women with each passing moon cycle. This is our power. This is why women were the first healers, mathematicians, economists, agriculturalists, astrologists. They understood the power of living with cycles. Their monthly menstrual cycle and the lunar cycle were their tools for understanding everything else in life.


HorMoon Awareness Guide


Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.