Holy Hormones Journal: Call it the evolution of reproductive medicine … but I call it messing with Mother Nature. Mitochondrial damage occurs as we age. The health of the mitochondria (the cell’s powerhouse) will influence one’s overall health, longevity – and now obviously fertility. It is obvious that damaged mitochondria is occurring at an earlier and earlier age… and may even be passed down genetically – opening the doors to a ‘brave new world’ of genetically modified babies.
But how do our mitochondria get damaged?
Lisa Bloomquist, who write for Hormones Matter – referenced this article in her post entitled: “The Fluoroquinolone Time Bomb – Answers in the Mitochondria.”
In “Mechanisms of Pathogenesis in Drug Hepatotoxicity Putting the Stress on Mitochondria” it is noted that:
…damage to mitochondria often reflects successive chemical insults, such that no immediate cause for functional changes or pathological alterations can be established. There is indeed experimental evidence that prolonged injury to mitochondria, such as that which typifies oxidative injury to mitochondrial DNA or to components of the electron transport chain (ETC), has to cross a certain threshold (or a number of thresholds) before cell damage or cell death becomes manifest.
Lisa goes on to explain:
Many pharmaceuticals damage mitochondria. Bactericidal antibiotics (including fluoroquinolones), Statins, acetamiphen, some chemotherapy drugs, vaccines, and many others, cause mitochondrial dysfunction, oxidative stress and cell death. Mitochondrial dysfunction and oxidative stress are connected to a variety of ailments, from chronic fatigue syndrome to Alzheimer’s disease and obesity. However, the FDA and other drug regulatory agencies have systematically ignored damage to mitochondria caused by pharmaceuticals and “mitochondrial toxicity testing is not required by the US FDA for drug approval.”
So the FDA has ignored the damage done to mitochondria from their own drugs and vaccines, yet they are allowing ‘reproductive IVF technology’ to walk through the door to manipulate our damaged mitochondria to create eugenic babies?
We now know that essential micronutrients absorbed at the cellular level can and will reverse mitochondrial damage.
Do women really need reproductive medicine to manipulate our eggs so we can produce genetically modified babies?
FDA panel debates technique that would create embryos with three genetic parents
The provocative notion of genetically modified babies met the very real world of federal regulation Tuesday, as a government advisory committee began debating a new technique that combines DNA from three people to create embryos free of certain inherited diseases. The two-day meeting of the Food and Drug Administration panel is focused on a procedure that scientists think could help women who carry DNA mutations for conditions such as blindness and epilepsy. The process would let them have children without passing on those defects.
The debate over whether the technique — nicknamed “three-parent IVF” — should be allowed to proceed to human tests underscores how quickly the science of reproductive medicine is evolving. Scientists argue that this technology, like cloning and embryonic stem cell research, has huge potential to help people. But it is also highly sensitive, touching ethical and political nerves.
The technology involves taking defective mitochondria, the cell’s powerhouses, from a mother’s egg and replacing them with healthy mitochondria from another woman. After being fertilized by the father’s sperm in a lab, the egg would be implanted in the mother, and the pregnancy could progress normally.The procedure was pioneered by Shoukhrat Mitalipov, a researcher at Oregon Health and Science University who focuses on early embryo development and stem cell biology. He has been able to produce five healthy monkeys using this technique and has proposed testing it in humans.Read full article…
The Controversy Continues
On March 8, BioEdge editor, Michael Cook updated his article to state in the latest newsletter that three-parent IVF – may already be ‘old hat’ as bio-science is now paving the way for IVG: “In Vitro Generated Gametes,” also known as ‘multiplex parenting’. Stop fretting about 3-parent embryos and get ready for “multiplex parenting.”
According to Cook, …one of Britain’s best known bioethicists, “John Harris, of the University of Manchester, and two colleagues, César Palacios-González and Giuseppe Testa contend in the Journal of Medical Ethics (free online) that this is one of many exciting consequences of using stem cells to create synthetic eggs and sperm. (Or as they prefer to call them, in vitro generated gametes (IVG).)
“Cook then asks the question is this ethical?
“Of course it is, so long as experiments on mice show that it is safe. After all, they write, this is already a much higher ethical bar than the one used for the first IVF babies. “If impractically high precautionary thresholds were decisive we would not have vaccines, nor IVF, nor any other advance. Nothing is entirely safe.” Besides, any children brought into the world are better off than if they never existed.”
“Any children brought into the world are better off than if they never existed?” Serious? Hmm – I think parent’s and children who suffer from genetic damage are the one’s best prepared to answer that question.