A Johns Hopkins Children’s Center study in mice may help explain why women are more prone than men to a form of liver damage by implicating the female sex hormone estrogen in the development of autoimmune hepatitis.
In addition to the traditionally acknowledged risk factors for breast cancer (age, reproductive history, genetic profile, obesity, alcohol intake, smoking, etc.), scientists are increasingly coming to understand that many chemicals commonly found in products we use daily may also be contributing to the very high incidence of breast cancer.
Excess estrogen levels during pregnancy can disable, in their daughters, a powerful breast cancer tumor suppressor gene, say researchers at Georgetown Lombardi Comprehensive Cancer Center. They found the DNA repair gene BRCA1 to be silenced in one year-old girls exposed to a high hormonal fetal environment.
Estrogen plus progestin use is linked with increased breast cancer incidence. In addition, prognosis is similar for both users and nonusers of combined hormone therapy, suggesting that mortality from breast cancer may be higher for hormone therapy users as well, according to a study published March 29 in the Journal of the National Cancer Institute.
Sound fishy you say? Not so – the amount of estrogen mimickers that are getting into the water streams is alarming and causing the feminization of male fish. Not just for estrogen in birth control – as we were told years ago – but now from a variety of products that we use on a daily basis. The biggest culprit is BPA in plastic. How many water bottles, food wrapping and even fishing equipment (plastic bob) are tossed into the water?
Our purpose here first is to put women’s midlife concerns into a new and more accurate hormonal picture. Specifically, I’d like to present new information about high estrogen levels in the perimenopause. Not low, not even normal, but estrogen levels that are higher than those of the (sexiest) 20 year old female!
Holy Hormones Honey! If you want to have a clear understanding on the role of reproductive hormones in your body – and how an imbalance between progesterone, estrogen and testosterone can wreak havoc physically, mentally and emotionally – listen to this informative interview with endocrinologist, Dr. Margarita Ochoa- Maya.
Another possible cause of cardiac syndrome X is changing oestrogen levels — menopausal women are particularly at risk of the condition, explains Professor Collins.
‘This condition affects around nine women for every one man,’ he explains.
‘The peak ages affected are 50 to 55-year-olds, around the time of the menopause.