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	<title>Holy Hormones, Honey! &#187; Plastics</title>
	<atom:link href="http://holyhormones.com/tag/plastics/feed/" rel="self" type="application/rss+xml" />
	<link>http://holyhormones.com</link>
	<description>The Greatest Story Never Told</description>
	<lastBuildDate>Wed, 08 Sep 2010 04:06:43 +0000</lastBuildDate>
	
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		<title>Toxic Baby Bottles: A Risk of Cancer</title>
		<link>http://holyhormones.com/womens-health/toxic-baby-bottles-a-risk-of-cancer/</link>
		<comments>http://holyhormones.com/womens-health/toxic-baby-bottles-a-risk-of-cancer/#comments</comments>
		<pubDate>Sun, 10 Jan 2010 02:28:14 +0000</pubDate>
		<dc:creator>Leslie Carol Botha</dc:creator>
				<category><![CDATA[Environmental Health]]></category>
		<category><![CDATA[Pregnancy]]></category>
		<category><![CDATA[Women's Health]]></category>
		<category><![CDATA[BPA]]></category>
		<category><![CDATA[Plastics]]></category>

		<guid isPermaLink="false">http://holyhormones.com/?p=4496</guid>
		<description><![CDATA[EmpowHer
January 5, 2010

Did you know that a common chemical used in the manufacture of plastics has been linked with cancer and numerous other conditions? The chemical, Bisphenol-A, or BPA, has been used to make plastic baby bottles for decades and has put billions of people throughout the world, who were bottle fed, at risk of cancer, hormone disorders and infertility.

BPA is in many other products from DVD's to resin, but its use in baby bottles is particularly concerning because when BPA heats up, it can leach out of the bottle and end up in formula milk to be ingested by the baby, causing tissue damage, hormone disruption and increasing the risk of developing cancer in later life.
]]></description>
			<content:encoded><![CDATA[<h3><a href="http://www.empowher.com/news/herarticle/2010/01/05/toxic-baby-bottles-risk-cancer" target="_blank">EmpowHer</a></h3>
<p>January 5, 2010</p>
<p>Did you know that a common chemical used in the manufacture of plastics has been linked with <a title="Read more about cancer" href="http://www.empowher.com/condition/cancer" target="_blank">cancer</a> and numerous other conditions? The chemical, Bisphenol-A, or BPA, has been used to make plastic baby bottles for decades and has put billions of people throughout the world, who were bottle fed, at risk of <a title="Read more about cancer" href="http://www.empowher.com/condition/cancer" target="_blank">cancer</a>, hormone disorders and infertility.</p>
<p>BPA is in many other products from DVD&#8217;s to resin, but its use in baby bottles is particularly concerning because when BPA heats up, it can leach out of the bottle and end up in formula milk to be ingested by the baby, causing tissue damage, hormone disruption and increasing the risk of developing <a title="Read more about cancer" href="http://www.empowher.com/condition/cancer" target="_blank">cancer</a> in later life.</p>
<p>While much thought has been given to the immunological and psychological benefits of breast feeding, little consideration has been given to the impact of using plastic bottles to feed a baby.</p>
<p>What is an endocrine disruptor?</p>
<p><a href="http://www.empowher.com/news/herarticle/2010/01/05/toxic-baby-bottles-risk-cancer" target="_blank">MORE&#8230;</a></p>
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		<item>
		<title>232 Toxic Chemicals found in 10 Babies</title>
		<link>http://holyhormones.com/hormone-cycles/estrogen/232-toxic-chemicals-found-in-10-babies/</link>
		<comments>http://holyhormones.com/hormone-cycles/estrogen/232-toxic-chemicals-found-in-10-babies/#comments</comments>
		<pubDate>Sun, 03 Jan 2010 19:45:16 +0000</pubDate>
		<dc:creator>Leslie Carol Botha</dc:creator>
				<category><![CDATA[Environmental Health]]></category>
		<category><![CDATA[Estrogen]]></category>
		<category><![CDATA[Hormones]]></category>
		<category><![CDATA[Pregnancy]]></category>
		<category><![CDATA[Teen Pregnancy]]></category>
		<category><![CDATA[Women's Politics]]></category>
		<category><![CDATA[BPA]]></category>
		<category><![CDATA[Breast Cancer]]></category>
		<category><![CDATA[Plastics]]></category>

		<guid isPermaLink="false">http://holyhormones.com/?p=4438</guid>
		<description><![CDATA[Mercola.com

Posted by: Dr. Mercola
December 31 2009

Laboratory tests commissioned by the Environmental Working Group have detected bisphenol A (BPA), a plastic component and synthetic estrogen, in umbilical cord blood of American infants.

Nine of 10 randomly selected samples of cord blood tested positive for BPA, an industrial petrochemical.
]]></description>
			<content:encoded><![CDATA[<h3><a href="http://articles.mercola.com/sites/articles/archive/2009/12/31/232-Toxic-Chemicals-found-in-10-Babies.aspx" target="_blank">Mercola.com</a></h3>
<p>Posted by:             <a href="http://articles.mercola.com/members/Dr.-Mercola/default.aspx" target="_blank">Dr. Mercola</a><br />
December 31 2009</p>
<p>Laboratory tests commissioned by the Environmental Working Group have detected bisphenol A (BPA), a plastic component and synthetic estrogen, in umbilical cord blood of American infants.</p>
<p>Nine of 10 randomly selected samples of cord blood tested positive for BPA, an industrial petrochemical.</p>
<p>BPA has been implicated in a lengthening list of serious chronic disorders, including cancer, cognitive and behavioral impairments, endocrine system disruption, reproductive and cardiovascular system abnormalities, diabetes, asthma and obesity.</p>
<p>In all, the tests found as many as 232 chemicals in the 10 newborns, all of minority descent. The cord blood study has produced hard new evidence that American children are being exposed, beginning in the womb, to complex mixtures of dangerous substances that may have lifelong consequences.</p>
<p>And in a separate study, researchers found that complications of pregnancy, such as preterm labor, preterm birth, and infection were lowest in women with the highest vitamin D levels.</p>
<p>Blood levels of activated vitamin D usually rise during very early pregnancy, and some of it crosses the placenta to bathe the fetus, especially the developing fetal brain, in activated vitamin D. But many &#8212; in fact most &#8212; pregnant women do not make as much vitamin D as they need.</p>
<p>4,000 IU of vitamin D per day during pregnancy was found to be safe (not a single adverse event). However, this amount only resulted in a mean vitamin D blood level of 27 ng/ml in the newborn infants, indicating that even 4,000 IU per day during pregnancy is not enough.</p>
<p><a href="http://articles.mercola.com/sites/articles/archive/2009/12/31/232-Toxic-Chemicals-found-in-10-Babies.aspx" target="_blank">MORE&#8230;</a></p>
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		<item>
		<title>Sex and BPA Don&#8217;t Mix, Say Researchers</title>
		<link>http://holyhormones.com/hormone-cycles/estrogen/sex-and-bpa-dont-mix-say-researchers/</link>
		<comments>http://holyhormones.com/hormone-cycles/estrogen/sex-and-bpa-dont-mix-say-researchers/#comments</comments>
		<pubDate>Thu, 12 Nov 2009 05:29:47 +0000</pubDate>
		<dc:creator>Leslie Carol Botha</dc:creator>
				<category><![CDATA[Estrogen]]></category>
		<category><![CDATA[Hormone Cycles]]></category>
		<category><![CDATA[Hormone Imbalance]]></category>
		<category><![CDATA[Men]]></category>
		<category><![CDATA[Sexual Health]]></category>
		<category><![CDATA[Testosterone]]></category>
		<category><![CDATA[Wellness]]></category>
		<category><![CDATA[BPA]]></category>
		<category><![CDATA[Plastics]]></category>

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		<description><![CDATA[US News World Report

November 11, 2009 11:10 AM ET &#124; Ford Vox

Bisphenol-A, better known as BPA, is the building block of polycarbonates and epoxy resins, plastics that have facilitated modern life. (They're in microwave containers, baby bottles, laptops, and even canned foods.) Tiny amounts circulate in the bodies of more than 90 percent of Americans. And now a team of Chinese and U.S. scientists says it has linked the stuff to sexual dysfunction in men. Even before today's news, plenty of people were getting the willies about BPA. Should this news make you feel less virile? Let's take a closer look.
]]></description>
			<content:encoded><![CDATA[<h3><a href="http://health.usnews.com/blogs/on-men/2009/11/11/sex-and-bpa-dont-mix-say-researchers.html" target="_blank">US News World Report</a></h3>
<p>November 11, 2009                            11:10 AM ET |                                                              <a href="http://www.usnews.com/Topics/tag/Author/f/ford_vox/index.html" target="_blank"> Ford Vox</a></p>
<p>Bisphenol-A, better known as BPA, is the building block of polycarbonates and epoxy resins, plastics that have facilitated modern life. (They&#8217;re in microwave containers, <a href="http://health.usnews.com/articles/health/living-well-usn/2008/04/16/study-of-chemical-in-plastic-bottles-raises-alarm.html" target="_blank">baby bottles</a>, laptops, and even <a href="http://health.usnews.com/articles/health/2008/04/18/controversial-plastic-chemical-is-in-canned-food-too.html" target="_blank">canned foods</a>.) Tiny amounts circulate in the bodies of more than 90 percent of Americans. And now a team of Chinese and U.S. scientists says it has linked the stuff to sexual dysfunction in men. Even before today&#8217;s news, <a href="http://health.usnews.com/articles/health/healthday/2009/06/10/studies-report-more-harmful-effects-from-bpa.html" target="_blank">plenty of people were getting the willies about BPA</a>. Should this news make you feel less virile? Let&#8217;s take a closer look.</p>
<p>Six years ago, De-Kun Li, a senior scientist at <a id="KonaLink0" class="kLink" style="text-decoration: underline ! important; position: static;" href="http://health.usnews.com/blogs/on-men/2009/11/11/sex-and-bpa-dont-mix-say-researchers.html#" target="undefined"><span style="color: #005497 ! important; font-weight: 400; font-size: 12px; position: static;"><span class="kLink" style="color: #005497 ! important; font-family: Georgia,&quot;Times New Roman&quot;,Times,serif; font-weight: 400; font-size: 12px; position: static;">Kaiser </span><span class="kLink" style="color: #005497 ! important; font-family: Georgia,&quot;Times New Roman&quot;,Times,serif; font-weight: 400; font-size: 12px; position: static;">Permanente&#8217;s</span></span></a> research arm, and his colleagues were already alarmed about BPA because of a steady stream of studies showing that BPA alters tissues in the reproductive organs and offspring of rats and mice. But there&#8217;s a heated debate among statisticians, toxicologists, and endocrinologists about which animal models are relevant to human disease and about the paradoxical way BPA seems to work. Unlike typical poisons or carcinogens, more is not always worse and less is not always better. In many of the studies, BPA changes animal tissues only at specific low concentrations and only at particular stages of the life cycle.</p>
<p>&#8220;BPA is not a toxin. It&#8217;s not going to kill you,&#8221; Li told me in an interview. It&#8217;s a form of artificial <a id="KonaLink1" class="kLink" style="text-decoration: underline ! important; position: static;" href="http://health.usnews.com/blogs/on-men/2009/11/11/sex-and-bpa-dont-mix-say-researchers.html#" target="undefined"><span style="color: #005497 ! important; font-weight: 400; font-size: 12px; position: static;"><span class="kLink" style="color: #005497 ! important; font-family: Georgia,&quot;Times New Roman&quot;,Times,serif; font-weight: 400; font-size: 12px; position: static;">estrogen</span></span></a> that could disrupt the endocrine system, where hormone signals like estrogen and testosterone subtly influence the behavior of cells throughout our bodies. Extra estrogen in females isn&#8217;t good (it&#8217;s known to increase breast cancer risk, for example), and it can interfere with testosterone in men.</p>
<p>But there&#8217;s precious little demonstration that this is happening in people and not just in lab animals. &#8220;The argument ultimately comes down to: &#8216;Where is the human evidence?&#8217; &#8221; says Li. That poses a dilemma. Li believes animal evidence alone won&#8217;t overcome industry&#8217;s vigorous defenses or satisfy government regulators—but he knows no university oversight panel will ever approve human BPA experiments.</p>
<p>Li did the next best thing, finding four factories in China where large quantities of BPA are generated (directly or in producing other materials) and studying the men who worked there. If BPA isn&#8217;t dangerous in such places, he figured, we don&#8217;t need to worry. He split up the exposed workers into three levels based on personal air sample monitors, job roles, and length of employment, and confirmed with air and urine sampling that they were exposed to much higher levels of BPA than similar men in the same city who didn&#8217;t work at the factories.</p>
<p>The research identified a pattern: Higher exposures led to more sexual frustration. The men in the factories had four times the rate of <a href="http://www.usnews.com/articles/health/sexual-reproductive/2008/08/14/about-erectile-dysfunction.html">erectile dysfunction</a> of the men who didn&#8217;t work there. They complained about ejaculation problems seven times as much. And overall, they were four times as likely to be disappointed with their sex life.</p>
<p><a href="http://health.usnews.com/blogs/on-men/2009/11/11/sex-and-bpa-dont-mix-say-researchers.html" target="_blank">MORE&#8230;</a></p>
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		<title>Chemical used in baby bottles create fertility issue</title>
		<link>http://holyhormones.com/womens-health/chemical-used-in-baby-bottles-create-fertility-issue/</link>
		<comments>http://holyhormones.com/womens-health/chemical-used-in-baby-bottles-create-fertility-issue/#comments</comments>
		<pubDate>Thu, 16 Jul 2009 12:37:53 +0000</pubDate>
		<dc:creator>Leslie Carol Botha</dc:creator>
				<category><![CDATA[Environmental Health]]></category>
		<category><![CDATA[Infertility]]></category>
		<category><![CDATA[Mothers & Daughters]]></category>
		<category><![CDATA[Pregnancy]]></category>
		<category><![CDATA[Women's Health]]></category>
		<category><![CDATA[BPA]]></category>
		<category><![CDATA[Plastics]]></category>

		<guid isPermaLink="false">http://holyhormones.com/?p=2747</guid>
		<description><![CDATA[Puppet Gov

Posted by PUPPETGOV on Jul 13th, 2009

BY MONIFA THOMAS~Chicago Suntimes

Exposure to Bisphenol A, a chemical widely used in plastics, may impair the growth and function of female reproductive cells in mice, a new study from the University of Illinois has found.

Previous lab tests in animals have linked BPA to adverse effects in fetuses and newborns, raising concerns about similar effects in people.
]]></description>
			<content:encoded><![CDATA[<h3><a href="http://blog.puppetgov.com/2009/07/13/chemical-used-in-baby-bottles-create-fertility-issue/" target="_blank">Puppet Gov</a></h3>
<p>Posted by  <a title="Posts by PUPPETGOV" href="http://blog.puppetgov.com/author/admin/">PUPPETGOV</a> on Jul 13th, 2009</p>
<p><strong>BY MONIFA THOMAS~<a href="http://www.suntimes.com/lifestyles/health/1663138,CST-NWS-plastic13.article" target="_blank">Chicago Suntimes </a></strong></p>
<p>Exposure to Bisphenol A, a chemical widely used in plastics, may impair the growth and function of female reproductive cells in mice, a new study from the University of Illinois has found.</p>
<p>Previous lab tests in animals have linked BPA to adverse effects in fetuses and newborns, raising concerns about similar effects in people.</p>
<p>Now, researchers from the U. of I.’s Urbana-Champaign campus have found that BPA appears to stunt the growth of follicles in the ovaries of adult female mice. The study is the first to show that chronic exposure to low doses of BPA can impair the growth and function of adult reproductive cells.</p>
<p>Follicles need to grow to maturity in order for ovulation to occur. They also stimulate the production of vital sex hormones such as estrogen and progesterone.</p>
<p>U. of I. veterinary biosciences professor Jodi Flaws found that mouse follicle cells exposed to a relatively low dose of BPA for at least 120 hours produced 95 percent less testosterone and 97 percent less progesterone.</p>
<p>Flaws will present her research later this month at the annual meeting of the Society for the Study of Reproduction.</p>
<p>She cautioned that further study is needed to determine if BPA would have the same effect on human reproduction and at what level of exposure.</p>
<p><a href="http://blog.puppetgov.com/2009/07/13/chemical-used-in-baby-bottles-create-fertility-issue/" target="_blank">MORE&#8230;</a></p>
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		<item>
		<title>BPA linked to cell damage in post-menopausal women but not men, younger women.</title>
		<link>http://holyhormones.com/menopause/bpa-linked-to-cell-damage-in-post-menopausal-women-but-not-men-younger-women/</link>
		<comments>http://holyhormones.com/menopause/bpa-linked-to-cell-damage-in-post-menopausal-women-but-not-men-younger-women/#comments</comments>
		<pubDate>Tue, 14 Jul 2009 12:53:01 +0000</pubDate>
		<dc:creator>Leslie Carol Botha</dc:creator>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[Environmental Health]]></category>
		<category><![CDATA[Menopause]]></category>
		<category><![CDATA[Post Menopausal Women]]></category>
		<category><![CDATA[Women's Health]]></category>
		<category><![CDATA[BPA]]></category>
		<category><![CDATA[Plastics]]></category>

		<guid isPermaLink="false">http://holyhormones.com/?p=2720</guid>
		<description><![CDATA[Environmental Health News
July 13, 2009

Yang YJ, YC Hong, SY Oh, MS Park, H Kim, JH Leem, and EH Ha. 2009. Bisphenol A exposure is associated with oxidative stress and inflammation in postmenopausal women. Environmental Research http://dx.doi.org/10.1016/j.envres.2009.04.014.

Synopsis by Michele A. La Merrill, Ph.D. and Wendy Hessler

Women in menopause are more prone to the BPA-associated health effects of inflammation and oxidative stress than either men or women who are still menstruating, finds this study of Korean adults. This is the first time BPA has been linked to these conditions in people and suggests older women may be more susceptible to the chemical's estrogen-like manner that drives these particular types of cell damage. Oxidative stress can be involved with aging, cancer and other disease states.]]></description>
			<content:encoded><![CDATA[<h3><a href="http://www.environmentalhealthnews.org/ehs/newscience/bpa-linked-to-cell-damage-in-post-menopausal-women-but-not-men-younger-women" target="_blank">Environmental Health News </a></h3>
<p>July 13, 2009</p>
<p>Yang YJ, YC Hong, SY Oh, MS Park, H Kim, JH Leem, and EH Ha. 2009. <strong>Bisphenol A exposure is associated with oxidative stress and inflammation in postmenopausal women</strong>. <a href="http://dx.doi.org/10.1016/j.envres.2009.04.014" target="_blank">Environmental Research http://dx.doi.org/10.1016/j.envres.2009.04.014</a><a href="http://dx.doi.org/10.1016/j.envres.2009.04.014." target="_blank">.</a></p>
<p>Synopsis by     <a href="http://">Michele A. La Merrill, Ph.D.</a> and <a href="http://www.environmentalhealthnews.org/ehs/Members/whessler" target="_blank">Wendy Hessler</a></p>
<p><span>Women in menopause are more prone to the BPA-associated health effects of inflammation and oxidative stress than either men or women who are still menstruating, finds this study of Korean adults. This is the first time BPA has been linked to these conditions in people and suggests older women may be more susceptible to the chemical&#8217;s estrogen-like manner that drives these particular types of cell damage. Oxidative stress can be involved with aging, cancer and other disease states.</span></p>
<div id="do">
<h2><a name="do">What did they do?</a></h2>
<p>The authors evaluated inflammation and oxidative stress markers in the blood of adult Koreans and then compared them to BPA measured in their urine. They examined the measurements in three groups: men, premenopausal women and postmenopausal women.</p>
<p>The urine and blood samples were collected from the participants at the same time. Two markers of oxidative stress – malondialdehyde and 8-hydroxydeoxyguanosine – and two markers of inflammation – white blood cells and C-reactive protein – were measured.</p>
<p>Questionnaires were administered to gather medical, lifestyle, exposure and demographic information.</p>
<p>Scientists know that inflammation and oxidative stress increase with age. The authors statistically controlled for age so they could see BPA effects independent of age. They also controlled for body mass and possible factors identified elsewhere that could influence oxidative stress.</p>
<p>The study included 259 men, 92 premenopausal women and 134 post-menopausal women.</p></div>
<h3><a name="find">What did they find?</a></h3>
<p>BPA was found in the urine of 76 percent of the Korean adults in this study. Concentrations were similar among groups for all levels except those with the highest measured amounts, where men had three times the levels of premenopausal women (26.5 versus 7.72 micrograms/gram) and about 50% more than postmenopausal women (17.90 microg/g).</p>
<p>Urine levels of bisphenol A were higher in older adults.</p>
<p>Associations between BPA levels and both oxidative stress and inflammation only occurred in postmenopausal women. Oxidative stress levels were higher in older women who also had higher levels of BPA. Further, levels of the inflammation-marker C- reactive protein was increased in the women with higher levels of BPA.</p>
<p><a href="http://www.environmentalhealthnews.org/ehs/newscience/bpa-linked-to-cell-damage-in-post-menopausal-women-but-not-men-younger-women" target="_blank">MORE&#8230;</a></p>
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		<title>Fun for the Whole Family: Girls Can Now Expect Longer Puberty</title>
		<link>http://holyhormones.com/hormone-cycles/estrogen/fun-for-the-whole-family-girls-can-now-expect-longer-puberty/</link>
		<comments>http://holyhormones.com/hormone-cycles/estrogen/fun-for-the-whole-family-girls-can-now-expect-longer-puberty/#comments</comments>
		<pubDate>Wed, 06 May 2009 21:42:08 +0000</pubDate>
		<dc:creator>Leslie Carol Botha</dc:creator>
				<category><![CDATA[Adolescent Girls]]></category>
		<category><![CDATA[Birth Control Pills/BCP's]]></category>
		<category><![CDATA[Breast Health]]></category>
		<category><![CDATA[Estrogen]]></category>
		<category><![CDATA[Hormone Cycles]]></category>
		<category><![CDATA[Hormones]]></category>
		<category><![CDATA[Menstrual Cycle]]></category>
		<category><![CDATA[Mothers & Daughters]]></category>
		<category><![CDATA[Puberty]]></category>
		<category><![CDATA[Wellness]]></category>
		<category><![CDATA[BPA]]></category>
		<category><![CDATA[Breast Cancer]]></category>
		<category><![CDATA[Menstruation]]></category>
		<category><![CDATA[Plastics]]></category>

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		<description><![CDATA[The Huffington Post
Charlotte Hilton Andersen

Runs the health and fitness site The Great Fitness Experiment
Posted May 6, 2009 &#124; 04:36 PM (EST)

In what had to be one of the most awkward studies to both participate in and administer, Danish researchers studied the onset of breast development in 2,095 European girls. Let's hope that was self-reported. All pedophilic weirdness aside, the researchers found something very interesting: the average age of breast development in European girls has dropped one year, from 10.8 to 9.8 years.]]></description>
			<content:encoded><![CDATA[<p class="float_left fixed_width_author">
<h3><a href="http://www.huffingtonpost.com/charlotte-hilton-andersen/fun-for-the-whole-family_b_196474.html" target="_blank">The Huffington Post</a></h3>
<address> </address>
<address><a href="http://www.huffingtonpost.com/charlotte-hilton-andersen" target="_blank">Charlotte Hilton Andersen</a></address>
<p class="teaser_permalink">Runs the health and fitness site The Great Fitness Experiment<br />
Posted May  6, 2009                                  					<span class="sep">|</span> 04:36 PM                                  (EST)</p>
<p>In what had to be one of the most awkward studies to both participate in and administer, <a href="http://well.blogs.nytimes.com/2009/05/04/earlier-puberty-in-european-girls/" target="_blank">Danish researchers studied the onset of breast development in 2,095 European girls</a>. Let&#8217;s hope that was self-reported. All pedophilic weirdness aside, the researchers found something very interesting: the average age of breast development in European girls has dropped one year, from 10.8 to 9.8 years.</p>
<p>As a girl who didn&#8217;t develop breasts until about 16 &#8212; and even then that point could be argued (I love you Victoria&#8217;s Secret gel bras!) &#8212; the thought of 9-year-olds with boobs was shocking enough to me. The researchers, however, not caring about my chest size or lack thereof, were concerned because breast development is one of the earliest signs of puberty in girls and the marked decrease has implications far beyond training bras next to the Littlest Pet Shop display.</p>
<p>After controlling for BMI and the age of menarche (hello Aunt Flo!), the researchers discovered that neither body weight nor menstruation was causing the earlier breast development. Which leaves us with two serious implications:</p>
<p>1) The environment, particularly estrogenic compounds like the much vilified bisphenol-A (BPA), is affecting girls&#8217; hormonal development. While this has largely been speculated previously and more research would be needed to proclaim a direct link, this research does lend some credence to this theory.</p>
<p>2) While the average age of menstruation has held steady for the past 50 or so years at about 12 years of age, puberty as defined by breast development begins earlier, meaning girls now endure a longer period of awkwardness and angst. And to anyone who thinks my use of &#8220;endure&#8221; to be hyperbolic, well, you have obviously never been a girl in the throes of puberty.</p>
<p><a href="http://www.huffingtonpost.com/charlotte-hilton-andersen/fun-for-the-whole-family_b_196474.html" target="_blank">MORE&#8230;</a></p>
<p><em>Make sure that you read the rest of the article &#8211; it states that early puberty not only leads to depression of young girls but it could also be a precursor of higher breast cancer risk in adulthood.</em></p>
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		<title>Hormonal Headaches Explored</title>
		<link>http://holyhormones.com/hormone-cycles/estrogen/hormonal-headaches-explored/</link>
		<comments>http://holyhormones.com/hormone-cycles/estrogen/hormonal-headaches-explored/#comments</comments>
		<pubDate>Sun, 03 May 2009 17:26:10 +0000</pubDate>
		<dc:creator>Leslie Carol Botha</dc:creator>
				<category><![CDATA[Acne]]></category>
		<category><![CDATA[Adolescent Girls]]></category>
		<category><![CDATA[Bioidentical Hormones]]></category>
		<category><![CDATA[Estrogen]]></category>
		<category><![CDATA[Hormone Cycles]]></category>
		<category><![CDATA[Hormone Imbalance]]></category>
		<category><![CDATA[Hormones]]></category>
		<category><![CDATA[Menstrual Cycle]]></category>
		<category><![CDATA[Migraines]]></category>
		<category><![CDATA[Mothers & Daughters]]></category>
		<category><![CDATA[Natural Progesterone]]></category>
		<category><![CDATA[PMDD]]></category>
		<category><![CDATA[PMS]]></category>
		<category><![CDATA[Periods]]></category>
		<category><![CDATA[Premenstrual Syndrome]]></category>
		<category><![CDATA[Premenstrual Tension]]></category>
		<category><![CDATA[Sexual Health]]></category>
		<category><![CDATA[Teens]]></category>
		<category><![CDATA[Women's Health]]></category>
		<category><![CDATA[BPA]]></category>
		<category><![CDATA[Estrogen Dominance]]></category>
		<category><![CDATA[Plastics]]></category>

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		<description><![CDATA[Health &#038; Wellness Digest

Posted by hwd editor in Headache on May 3, 2009 &#124;

Hormonal headaches are suffered by women and can take place during the menstrual cycle. Hormones are what induces the pain response so both men and hormones prompt women’s headaches. Headaches are sometimes our body using a warning system that something serious is going on. Hormones regulate and start many of the body’s functions, so it is not surprising that they are in some way connected to headaches.]]></description>
			<content:encoded><![CDATA[<h3><a href="http://www.healthwellnessdigest.com/hormonal-headaches-explored/" target="_blank">Health &amp; Wellness Digest</a></h3>
<p>Posted by hwd editor<br />
May 3, 2009</p>
<p>Hormonal headaches are suffered by women and can take place during the menstrual cycle. Hormones are what induces the pain response so both men and hormones prompt women’s headaches. Headaches are sometimes our body using a warning system that something serious is going on. Hormones regulate and start many of the body’s functions, so it is not surprising that they are in some way connected to headaches.</p>
<p>Menstrual migraines are hormonal headaches. Serotonin is one of the most common of the hormonal triggers. Women who suffer migraines may do so because of the way serotonin interacts with her female hormones. Menstrual migraines are caused by estrogen, which is the female sex hormone. They can get headaches when the estrogen and progesterone levels change in her cycle.</p>
<p>A woman may experience one-sided throbbing, accompanied by nausea, vomiting, or light sensitivity or sound sensitivity.</p>
<p>Women who suffer from Pre-Menstrual Syndrome (PMS) may also have hormonal headaches. These headaches happen before the period starts. The PMS headache may be accompanied by acne, joint pain, and fatigue. She may also experience an increased occurrence of fear, panic attacks, a decreased sexual desire, and she may also suffer from an impaired judgment or memory problems. She may seem to be paranoid or be more sensitive to rejection. Typically these symptoms disappear as soon as the menstrual cycle begins.</p>
<p><a href="http://www.healthwellnessdigest.com/hormonal-headaches-explored/" target="_blank">MORE&#8230;</a></p>
<p>Comment from Leslie</p>
<p><em>If you continue reading on with this article it will begin to discuss the different types of drugs that you can take for hormonal headaches.  Of course there are natural solutions so research those carefully too.</em></p>
<p><em>The bottom line is that when women do not live with the natural ebb and flow of  their hormone cycle &#8211; they will be putting a lot of undue stress on their endocrine system &#8211; and their emotions.  Please see <a href="http://holyhormones.com/female-mystique/" target="_blank">Female Mystique The Three Phases of Eve </a></em></p>
<p><em>My co-author and I just published our first e-book <a href="http://holyhormones.com/book-store/" target="_blank">&#8220;Understanding Your Mood, Mind and Hormone Cycle </a>and covers this information in a simple and meaningful way.</em></p>
<p><em>Most women are actually dehydrated and do not even realize it.  Hormonal headaches can also be a result of that.  Drinking plenty of water &#8211; not soda, coffee, juice or teas &#8211; just unfiltered water &#8211; AND NOT FROM A PLASTIC BOTTLE will also be helpful in easing headaches.</em></p>
<p><em>Of course, if a woman is estrogen dominate &#8211; as most are &#8211; using a natural progesterone cream will be helpful in balancing the hormones and easing the headache and other PMS discomforts.<br />
</em></p>
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		<title>Progesterone Infertility</title>
		<link>http://holyhormones.com/sister_song/progesterone-infertility/</link>
		<comments>http://holyhormones.com/sister_song/progesterone-infertility/#comments</comments>
		<pubDate>Sun, 03 May 2009 13:18:56 +0000</pubDate>
		<dc:creator>Leslie Carol Botha</dc:creator>
				<category><![CDATA[Adolescent Girls]]></category>
		<category><![CDATA[Bioidentical Hormones]]></category>
		<category><![CDATA[Cervarix]]></category>
		<category><![CDATA[Endometriosis]]></category>
		<category><![CDATA[Estrogen]]></category>
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		<category><![CDATA[Hormone Imbalance]]></category>
		<category><![CDATA[Hormones]]></category>
		<category><![CDATA[Infertility]]></category>
		<category><![CDATA[Menopause]]></category>
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		<category><![CDATA[My Sister's Song]]></category>
		<category><![CDATA[Natural Progesterone]]></category>
		<category><![CDATA[PMDD]]></category>
		<category><![CDATA[PMS]]></category>
		<category><![CDATA[Peri-Menopause]]></category>
		<category><![CDATA[Polycystic Ovarian Syndrome]]></category>
		<category><![CDATA[Post Menopausal Women]]></category>
		<category><![CDATA[Postpartum Depression]]></category>
		<category><![CDATA[Pregnancy]]></category>
		<category><![CDATA[Premenstrual Syndrome]]></category>
		<category><![CDATA[Premenstrual Tension]]></category>
		<category><![CDATA[Teens]]></category>
		<category><![CDATA[Vaccinations]]></category>
		<category><![CDATA[Women's Health]]></category>
		<category><![CDATA[BPA]]></category>
		<category><![CDATA[Estrogen Dominance]]></category>
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		<description><![CDATA[“Progesterone infertility can mean there's either an excess of estrogen, a condition called estrogen dominance, or there's a deficiency of progesterone. Progesterone and estrogen are two vital hormones to the life and well-being of every woman. However, progesterone is the hormone of fertility and pregnancy.”]]></description>
			<content:encoded><![CDATA[<div>
<h3><a href="http://onereachinganother.blogspot.com/" target="_blank">Finally A Mom &#8211; The struggles and triumph of overcoming infertility</a></h3>
<p><span style="color: #000080;">My name is Annetta Price, (affectionately called Marie). My husband and I suffered with infertility for over a decade. Early in our marriage, I was diagnosed with a common condition, known as Polycystic Ovarian Syndrome (PCOS), which resulted in infertility. My plan is to share with you my journey of struggles, anxiety, tears and disappointments and subsequently, the triumphant victory of finally becoming a mom.</span></div>
<div></div>
<div>In my research on the causes of infertility, Progesterone Infertility is never mentioned as one the more popular cases of infertility and as a result of this, it does not get the attention as the other more popular ones.</div>
<div><strong>What is Progesterone infertility?</strong></div>
<div><em></em></div>
<p><em><span style="font-size: 100%;"><em>“Progesterone infertility can mean there&#8217;s either an excess of estrogen, a condition called estrogen dominance, or there&#8217;s a deficiency of progesterone. Progesterone and estrogen are two vital hormones to the life and well-being of every woman. However, progesterone is the hormone of fertility and pregnancy.”</em> </span></em></p>
<div>
<p>Please click on the following links to continue reading about Progesterone infertility and how it can be treated using supplementary progesterone cream. I am not sure how available this product is worldwide, but it does not hurt to ask your doctor about this treatment.</p></div>
<div><a href="http://www.safemenopausesolutions.com/progesteronein%20http://www.yourlifesource.com/upfold/natural-progesterone-fertility.htmfertility.html">http://www.safemenopausesolutions.com/progesteronein%20http://www.yourlifesource.com/</a></div>
<div><a href="http://www.safemenopausesolutions.com/progesteronein%20http://www.yourlifesource.com/upfold/natural-progesterone-fertility.htmfertility.html">upfold/natural-progesterone-fertility.htmfertility.html<br />
</a></div>
<div>If you have been diagnosed with infertility of this kind, the above sites will be helpful to you.<br />
Just a reminder of one important point I made in my infertility story. When you are diagnosed it is always beneficial to research as much as possible on your condition so that you will be able to contribute to your treatment process in a meaningful and informed manner. This can no doubt lead to a shorter and more productive treatment process so that your dreams of having the family you desire can become a reality much sooner.</div>
<div></div>
<div>Comment from Leslie</div>
<div></div>
<div><em>Progesterone Therapy could be considered for all the Gardasil girls that have become afflicted with PCOS &#8211; at such an early age. </em></div>
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		<title>Our Stolen Future &#8211; BPA Bisphenol A Levels in Plastic</title>
		<link>http://holyhormones.com/hormone-replacement-therapy/our-stolen-future-bpa-bisphenol-a-levels-in-plastic/</link>
		<comments>http://holyhormones.com/hormone-replacement-therapy/our-stolen-future-bpa-bisphenol-a-levels-in-plastic/#comments</comments>
		<pubDate>Wed, 15 Apr 2009 15:41:34 +0000</pubDate>
		<dc:creator>Leslie Carol Botha</dc:creator>
				<category><![CDATA[Bioidentical Hormones]]></category>
		<category><![CDATA[Birth Control Pills/BCP's]]></category>
		<category><![CDATA[Breast Health]]></category>
		<category><![CDATA[Cancer]]></category>
		<category><![CDATA[Estrogen]]></category>
		<category><![CDATA[Hormone Replacement Therapy]]></category>
		<category><![CDATA[Men]]></category>
		<category><![CDATA[Natural Progesterone]]></category>
		<category><![CDATA[Science]]></category>
		<category><![CDATA[Weight]]></category>
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		<category><![CDATA[Breast Cancer]]></category>
		<category><![CDATA[Fertility]]></category>
		<category><![CDATA[Immune System]]></category>
		<category><![CDATA[Infertility]]></category>
		<category><![CDATA[Obesity]]></category>
		<category><![CDATA[Plastics]]></category>
		<category><![CDATA[Reproduction]]></category>
		<category><![CDATA[Weight Gain]]></category>

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		<description><![CDATA[Our Stolen Future
While Bisphenol A was first synthesized in 1891, the first evidence of its estrogenicity came from experiments in the 1930&#8217;s feeding BPA to ovariectomised rats (Dodds and Lawson 1936, 1938). 
Another compound invented during that era, diethylstilbestrol, turned out to be more powerful as an estrogen, so bisphenol A was shelved&#8230; until polymer [...]]]></description>
			<content:encoded><![CDATA[<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><span class="OSFstandard"><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><strong><a href="http://www.ourstolenfuture.org/NewScience/oncompounds/bisphenola/bpauses.htm" target="_self">Our Stolen Future</a></strong></span></span></span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><span class="OSFstandard"><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">While Bisphenol A was first synthesized in 1891, the first evidence of its estrogenicity came from experiments in the 1930&#8217;s feeding BPA to ovariectomised rats (Dodds and Lawson 1936, 1938). </span></span></span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">Another compound invented during that era, diethylstilbestrol, turned out to be more powerful as an estrogen, so bisphenol A was shelved&#8230; until polymer chemists discovered that it could be polymerized to form polycarbonate plastic. Unfortunately, the ester bond that links BPA monomers to one another to form a polymer is not stable and hence the polymer decays with time, releasing BPA into materials with which it comes into contact, for example food or water. </span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">Bisphenol A is now deeply imbedded in the products of modern consumer society, not just as the building block for polycarbonate plastic (from which it then leaches as the plastic ages) but also in the manufacture of epoxy resins and other plastics, including polysulfone, alkylphenolic, polyalylate, polyester-styrene, and certain polyester resins.</span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">Its uses don&#8217;t end with the making of plastic. Bisphenol A has been used as an inert ingredient in pesticides (although in the US this has apparently been halted), as a fungicide, antioxidant, flame retardant, rubber chemical, and polyvinyl chloride stabilizer.</span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">These uses create a myriad of exposures for people. Bisphenol A-based polycarbonate is used as a plastic coating for children&#8217;s teeth to prevent cavities, as a coating in metal cans to prevent the metal from contact with food contents, as the plastic in food containers, refrigerator shelving, baby bottles, water bottles, returnable containers for juice, milk and water, micro-wave ovenware and eating utensils.</span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">Other exposures result from BPA&#8217;s use in &#8220;films, sheets, and laminations; reinforced pipes; floorings; watermain filters; enamels and vanishes; adhesives; artificial teeth; nail polish; compact discs; electric insulators; and as parts of automobiles, certain machines, tools, electrical appliances, and office automation instruments&#8221; (Takahashi and Oishi 2000). </span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">BPA contamination is also widespread in the environment. For example, BPA can be measured in rivers and estuaries at concentrations that range from under 5 to over 1900 nanograms/liter. Sediment loading can also be significant, with levels ranging from under 5 to over 100 µg/kg (ppb) BPA is quite persistent as under normal conditions in the environment it does not readily degrade (Rippen 1999).</span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><strong>What this all means is that most of your life you are within arm&#8217;s length or closer to bisphenol A</strong>. No wonder the debate over its toxicity is so intense.</span></p>
<p> <span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><strong>Some important recent studies of bisphenol A:</strong></span></p>
<p class="OSFstandard"><strong><strong><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><strong><strong><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><strong><strong><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><strong><strong></strong></strong></span></strong></strong></span></strong></strong></span></strong>Experiments with rats demonstrate that low level exposure to bisphenol A during fetal growth causes breast cancer in adults</strong>. At all levels tested down to 2.5 parts per billion, BPA induced formation of aberrant cell growth patterns associated in rodents and people with breast cancer. Levels only 5 times higher than EPA&#8217;s current safe level caused carcinoma in situ. Using these results to set safety standards would radically reduce use of BPA in plastics and resins. </p>
<p class="OSFstandard"><strong><strong><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><strong><strong><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><strong><strong><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><strong><strong></strong></strong><em>In utero</em> exposure to BPA causes long-term effects on mammary tissue development in rats, increasing risks to cancer, and also increases sensitivity to a chemical known to cause breast cancer. </span></strong></strong></span></strong></strong></span></strong></strong>The study strengthens support for a link between increasing rates of breast cancer in recent decades and increasing exposure to estrogenic chemicals like BPA. It also indicates that human epidemiological studies that fail to incorporate developmental exposures can&#8217;t be trusted to identify cancer-causing agents. More&#8230;</p>
<p class="OSFstandard"><strong><strong><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><strong><strong></strong>Perinatal exposure to extremely low levels of bisphenol A causes precancerous prostate lesions in rats. </strong></span></strong></strong><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">These lesions, called prostatic intraepithelial neoplasia, or PIN, are cancerous and are considered to be a precursor of metastatic prostate cancer in humans. One hundred percent of rats exposed perinatally and then, during adulthood, treated with estradiol and testosterone to create hormonal conditions analogous to thos of an ageing man, developed high-grade PIN. The effect appears to result from the failure in exposed animals of a gene to become hypermethylated as the rats aged. More&#8230;</span></p>
<p class="OSFstandard"><strong><strong><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><strong><strong></strong>Experiments with mice reveal that chronic adult exposure to bisphenol A causes insulin resistance. </strong></span></strong></strong><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">Insulin resistance in people leads to Type II diabetes and congestive heart failure, and is part of the modern epidemic of &#8216;metabolic syndrome.&#8217; The exposure levels used were within the range that people experience regularly. More&#8230;</span></p>
<p><span class="OSFstandard"><strong><strong></strong>In a small prospective study, researchers in Japan report that bisphenol A levels are higher in women with a history of repeated spontaneous miscarriages.</strong> This research was based on proof that BPA causes meiotic aneuploidy in mice. Meiotic aneuploidy is the commonest cause of miscarriage in people. The researchers also followed the pregnancies of the women to completion, and found evidence of aneuploidy in several of the miscarried fetuses.</span> More&#8230;</p>
<p class="OSFstandard"><strong>Bisphenol A and the birth control pharmaceutical ethinylestradiol cause adverse effects in prostate development in mice at levels to which millions of Americans are exposed each year</strong>. The results implicate these compounds in human prostate diseases, including prostate cancer. The research also shows the futility of predicting the developmental consequences of low-dose exposures based on high-dose experiments. More&#8230;</p>
<p class="OSFstandard"><strong>A flood of new information about bisphenol A revealing both widespread human exposure and effects at extremely low doses sparks a call for a new risk assessment of the ubiquitous compound</strong>. Bisphenol A, the basic building block of polycarbonate plastic, alters development of the reproductive tract, the immune system, increases prostate tumor proliferation, changes brain chemistry and structure and affects an array of behaviors, including hyperactivity. Of 11 studies of the compound&#8217;s effects at low doses, none funded by industry reported impacts. In contrast, 94 out of 104 government-funded studies found effects. This summary includes audio files of an international teleconference about bisphenol A. More&#8230;</p>
<p>S<span class="OSFstandard">everal &#8216;weakly&#8217; estrogenic compounds including bisphenol A and endosulfan are <strong>as powerful as estrogen at increasing calcium influx into cells and stimulating prolactin secretion</strong>. The effects are mediated by a cell membrane surface receptor instead of nuclear hormone receptors, the focus of most studies to date. Changes in calcium and prolactin occur at extremely low doses, well within the range of human exposures.</span> <span class="OSFreferences">Wozniak, AL, NN Bulayeva and CS Watson. 2005. Xenoestrogens at Picomolar to Nanomolar Concentrations Trigger Membrane Estrogen Receptor-alpha-Mediated Ca++ Fluxes and Prolactin Release in GH3/B6 Pituitary Tumor Cells. Environmental Health Perspectives, in press</span>.</p>
<p><strong>Bisphenol A at extremely low levels causes changes in brain structure and behavior in rats</strong>. The <span class="OSFstandard">locus coeruleus is believed to be a key brain center for anxiety and fear. Normally this is larger in females than in males. Rats exposed to BPA at levels beneath the current &#8217;safe&#8217; exposure level established by the US EPA show a reversal in sex dimorphism, with males&#8217; LC larger than females.&#8217; .</span> <span class="OSFreferences">Kubo, K, O Arai, M Omura, R Wantanabe, R Ogata, and S Aou. 2003. Low dose effects of bisphenol A on sexual differentiation of the brain and behavior in rats. Neuroscience Research 45: 345-356.</span></p>
<p><strong>Exposures to 1/5th the level considered safe are sufficient to alter maternal behavior in mice</strong>, including reductions in time spent nursing, increases in time resting away from offspring, and increases in time spent out of the nest. <span class="OSFreferences">Palanza, P, KL Howdeshell, S Parmigiani and FS vom Saal. 2002. Exposure to a low dose of bisphenol A during fetal life or in adulthood alters maternal behavior in mice. Environmental Health Perspectives 110 (suppl 3): 415-422.</span></p>
<p align="left"><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">An accident in the lab, followed by careful analysis and a series of experiments, reveals that <strong>bisphenol A causes aneuploidy in mice at low levels of exposure</strong>. Because aneuploidy in humans causes spontaneous miscarriages and some 10-20% of all birth defects, including Down Syndrome, this implicates bisphenol A in a broad range of human developmental errors<strong>.</strong> <span style="font-size: x-small;">Hunt, PA, KE Koehler, M Susiarjo, CA Hodges, A Ilagan, RC Voigt, S Thomas, BF Thomas and TJ Hassold. 2003. <strong>Bisphenol A exposure causes meiotic aneuploidy in the female mouse</strong>. Current Biology 13: 546-553.</span></span></p>
<p align="left"><span style="font-size: small; font-family: Verdana, Arial, Helvetica, sans-serif;">Experiments by researchers at the University of Missouri raise the possibility of <strong>widespread contamination of laboratory experiments by bisphenol A</strong>. Their results demonstrate that at room temperature significant amounts of this estrogenic substance leach into water from old polycarbonate animal cages. </span><span style="font-size: small; font-family: Verdana, Arial, Helvetica, sans-serif;">This inadvertent contamination could <strong>interfere with experiments designed to test the safety of estrogenic chemicals</strong>, and lead to false negatives and conflicting results</span><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><strong>.</strong> <span style="font-size: x-small;">Howdeshell, KA, PH Peterman, BM Judy, JA Taylor, CE Orazio, RL Ruhlen, FS vom Saal, and WV Welshons 2003. <strong>Bisphenol A is released from used polycarbonate animal cages into water at room temperature</strong>. Environmental Health Perspectives doi:10.1289/ehp.5993.</span></span></p>
<p align="left"><span style="font-size: small; font-family: Verdana, Arial, Helvetica, sans-serif;">An analysis of the biochemical mechanisms of endocrine disruption suggests why industry has been unable to replicate crucial low-dose impacts of bisphenol A on prostate development.</span><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"> <span style="font-size: x-small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">Welshons, WV, KA Thayer, BM Judy, JA Taylor, EM Curran and FS vom Saal. 2003.</span><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><span style="font-size: x-small;"> <strong>Large effects from small exposures. I. Mechanisms for endocrine disrupting chemicals with estrogenic activity</strong>. <em>Environmental Health Perspectives</em> doi:10.1289/ehp.5494</span></span> </span></p>
<p align="left"><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">Using new analytical methods, a team of German scientists measured <strong>bisphenol A in the blood of pregnant women, in umbilical blood at birth and in placental tissue</strong>. All samples examined contained BPA, at levels within the range shown to alter development. <strong>Thus widespread exposure to BPA at levels of concern is no longer a hypothetical issue. It is occurring.</strong> <span style="font-size: x-small;">Schönfelder, G, W Wittfoht, H Hopp, CE Talsness, M Paul and I Chahoud. 2002. <strong>Parent Bisphenol A Accumulation in the Human Maternal-Fetal-Placental Unit</strong>. <em>Environmental Health Perspectives</em> 110:A703-A707.</span></span></p>
<p align="left"><span style="font-size: x-small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><strong><span style="font-size: small;">At extremely low levels, BPA promotes fat cell (adipocyte) differentiation and accumulation of lipids</span></strong><span style="font-size: small;"> in a cell culture line used as a model for adipocyte formation. These two steps, differentiation and accumulation, are crucial in the development of human obesity. Hence this result opens up a whole new chapter in efforts to understand the origins of the world-wide obesity epidemic.</span> Masuno, H, T Kidani, K Sekiya, K Sakayama, T Shiosaka, H Yamamoto and K Honda. 2002. <strong>Bisphenol A in combination with insulin can accelerate the conversion of 3T3-L1 fibroblasts to adipocytes</strong>. <em>Journal of Lipid Research</em> 3:676-684.</span></p>
<p align="left"><span style="font-size: x-small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"><span style="font-size: small;">In cell culture experiments, <strong>BPA at very low (nanomolar levels) stimulates androgen-independent proliferation of prostate cancer cells</strong>. This finding is especially important because when prostate tumors become androgen-independent they no longer respond to one of the key therapies for prostate cancer. </span>Wetherill, YB, CE Petre, KR Monk, A Puga, and KE Knudsen. 2002. <strong>The Xenoestrogen Bisphenol A Induces Inappropriate Androgen Receptor Activation and Mitogenesis in Prostatic Adenocarcinoma Cells</strong>. <em>Molecular Cancer Therapeutics</em> 1: 515–524. </span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">BPA causes changes in rat ventral prostate cells that appear similar to events that <strong>make nascent prostate tumors</strong> in humans more potent:<span style="font-size: x-small;"> </span><span style="font-size: x-small;">Ramos, JG, J Varayoud, C Sonnenschein, AM Soto, M Muñoz de Toro and EH Luque. 2001. <strong>Prenatal Exposure to Low Doses of Bisphenol A Alters the Periductal Stroma and Glandular Cell Function in the Rat Ventral Prostate.</strong> <em>Biology of Reproduction</em> 65: 1271–1277.</span> </span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">BPA induces changes in mouse mammary tissue that resemble early stages <strong>mouse and human of breast cancer</strong>:<span style="font-size: x-small;"> Markey, CM, EH Luque, M Muñoz de Toro, C Sonnenschein and AM Soto</span></span><span style="font-size: x-small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">. 2001. <strong><em>In Utero</em> Exposure to Bisphenol A Alters the Development and Tissue Organization of the Mouse Mammary Gland</strong><strong>.</strong> <em>Biology of Reproduction</em> 65: 1215–1223. </span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">BPA lowers sperm count in adult rats even at extremely low levels:<span style="font-size: x-small;"> </span></span><span style="font-size: x-small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">Sakaue, M, S Ohsako, R Ishimura, S Kurosawa, M Kurohmaru, Y Hayashi, Y Aoki, J Yonemoto and C Tohyama. 2001. <strong>Bisphenol-A Affects Spermatogenesis in the Adult Rat Even at a Low Dose.</strong> Journal of Occupational Health 43:185 -190</span><span style="font-size: x-small;">.</span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">BPA at extremely low levels creates <strong>superfemale snails</strong>.</span><span style="font-size: x-small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"> Oehlmann, J, U Schulte-Oehlmann, M Tillmann and B Markert. 2000. <strong>Effects of endocrine disruptors on Prosobranch snails (Mollusca: Gastropoda) in the laboratory. Part I: Bisphenol A and Octylphenol as xenoestrogens</strong>. Ecotoxicology 9:383-397.</span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">BPA is<strong> rapidly transfered to the fetus </strong>after maternal uptake:</span><span style="font-size: x-small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"> </span><span style="font-size: x-small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">Takahashi, O and S Oishi. 2000. <strong>Disposition of Orally Administered 2,2-Bis(4-hydroxyphenyl) propane (Bisphenol A) in Pregnant Rats and the Placental Transfer to Fetuses</strong>. <em>Environmental Health Perspectives</em> 108:931-935. </span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">An independently funded, academic laboratory can <strong>verify controversial BPA results</strong>, even though industry can&#8217;t:<span style="font-size: x-small;"> </span></span><span style="font-size: x-small; font-family: Verdana, Arial, Helvetica, sans-serif;">Gupta, Chhanda. 2000. <strong>Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals</strong>. <em>Proceedings of the Society for Experimental Biology and Medicine</em> 224:61-68.</span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">Metabolic differences between rats and humans probably mean that <strong>humans are more sensitive to BPA</strong> than are rats:<span style="font-size: x-small;"> Elsby, R, JL Maggs, J Ashby and BK Park. 2001. <strong>Comparison of the modulatory effects of human and rat liver microsomal metabolism on the estrogenicity of bisphenol A: implications for extrapolation to humans</strong>. <em>Journal of Pharmacology and Experimental Therapeutics</em> 297-103-113. </span></span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">A <strong>confirmation of BPA low dose effects</strong>, and demonstration that the effects include impacts on estrous cyclicity and plasma LH levels:<span style="font-size: x-small;"> Rubin, BS, MK Murray, DA Damassa, JC King and AM Soto. 2001. <strong>Perinatal Exposure to Low Doses of Bisphenol A Affects Body Weight, Patterns of Estrous Cyclicity, and Plasma LH Levels</strong>. <em>Environmental Health Perspectives</em> 109: 675-680. </span></span></p>
<p><span style="font-size: small; color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;">BPA <strong>speeds the pace of sexual development</strong> in mice, and <strong>causes mice to be obese</strong>:<span style="font-size: x-small;"> </span></span><span style="font-size: x-small; font-family: Verdana, Arial, Helvetica, sans-serif;">Howdeshell, K, AK Hotchkiss, KA Thayer, JG Vandenbergh and FS vom Saal. 1999. <strong>Plastic bisphenol A speeds growth and puberty</strong>. <em>Nature</em> 401: 762-764</span><span style="font-size: x-small;">.<span style="color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif;"> </span></span></p>
<p><span style="font-size: x-small; font-family: Verdana;"><strong>Leslie&#8217;s Comments</strong></span></p>
<p><span style="font-size: x-small; font-family: Verdana;"><em>Using natural progesterone helps to balance the estrogen dominance so prevalent in our lives. See Dr. Judi Gerstung&#8217;s book on hormone balancing at </em><a href="http://www.estrogenissues.com"><em>http://www.estrogenissues.com</em></a></span></p>
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		<title>The Problem with Plastics</title>
		<link>http://holyhormones.com/hormone-cycles/estrogen/the-problem-with-plastics/</link>
		<comments>http://holyhormones.com/hormone-cycles/estrogen/the-problem-with-plastics/#comments</comments>
		<pubDate>Thu, 04 Sep 2008 23:47:36 +0000</pubDate>
		<dc:creator>Leslie Carol Botha</dc:creator>
				<category><![CDATA[Adolescent Girls]]></category>
		<category><![CDATA[Breast Health]]></category>
		<category><![CDATA[Education]]></category>
		<category><![CDATA[Estrogen]]></category>
		<category><![CDATA[Infertility]]></category>
		<category><![CDATA[Memory Loss]]></category>
		<category><![CDATA[Men]]></category>
		<category><![CDATA[Menopause]]></category>
		<category><![CDATA[Menstrual Cycle]]></category>
		<category><![CDATA[Mothers & Daughters]]></category>
		<category><![CDATA[Pregnancy]]></category>
		<category><![CDATA[Puberty]]></category>
		<category><![CDATA[Wellness]]></category>
		<category><![CDATA[Women's Health]]></category>
		<category><![CDATA[BPA]]></category>
		<category><![CDATA[Plastics]]></category>

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Posted on September 4th, 2008
by Nancy Reyes in All News, Breaking News, Business News, Country News, Economic News, Environmental News, Medical News, Research News, Science News, Society and Culture, US Government News, US News

One of the environmental stories that has worried some of us for years is again in the news.
There is a [...]]]></description>
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<div class="posted-aut-cat">Posted on September 4th, 2008</div>
<div class="posted-aut-cat">by <span style="color: #666666;">Nancy Reyes</span> in <span style="color: #666666;">All News</span>, <span style="color: #666666;">Breaking News</span>, <span style="color: #666666;">Business News</span>, <span style="color: #666666;">Country News</span>, <span style="color: #666666;">Economic News</span>, <span style="color: #666666;">Environmental News</span>, <span style="color: #666666;">Medical News</span>, <span style="color: #666666;">Research News</span>, <span style="color: #666666;">Science News</span>, <span style="color: #666666;">Society and Culture</span>, <span style="color: #666666;">US Government News</span>, <span style="color: #666666;">US News</span></div>
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<p>One of the environmental stories that has worried some of us for years is again in the news.</p>
<p>There is a new report that worries about the Bisphenol A, a chemical used to harden plastics including that found in water bottles and baby bottles, was found to cause<a href="http://www.efluxmedia.com/news_Bisphenol_A_Causes_Health_Issues_in_Primates_23653.html"><strong> brain changes in baby monkeys. </strong></a></p>
<blockquote><p>&#8220;The study was published in the Proceedings of the National Academy of Sciences and it looked at monkeys that had been exposed to bisphenol A levels that are considered harmless to humans by the Environmental Protection Agency. Results showed that the chemical interfered with brain cell connections vital to learning and memory.&#8221;</p></blockquote>
<p>Most toxicology studies are nonsense, since often the studies use huge doses of X and then activists cry out “BAD BAD”, while the chemical industry correctly points out that no one ever gets exposed to such a high does, and of course they can pressures the press and government to ignore the problem.</p>
<p>What is worrisome about this study is two things: The study used small amounts of the chemical, and another study showed that<a href="http://discovermagazine.com/2008/may/18-the-dirty-truth-about-plastic/article_print"><strong> heating water, or adding hot water to the plastic bottles increased the amount of BisphenolA in the liquid. </strong></a></p>
<p>And<a href="http://www.pnas.org/content/early/2008/09/02/0806139105.abstract"><strong> the BisphenolA and other plastics have properties that mimic female hormones,</strong></a> which gives one another reason to worry:</p>
<blockquote><p>&#8220;Our data indicate that even at this relatively low exposure level, BPA completely abolishes the synaptogenic response to estradiol. Because remodeling of spine synapses may play a critical role in cognition and mood, the ability of BPA to interfere with spine synapse formation has profound implications. This study is the first to demonstrate an adverse effect of BPA on the brain in a nonhuman primate model and further amplifies concerns about the widespread use of BPA in medical equipment, and in food preparation and storage.&#8221;</p></blockquote>
<p>Translation: BPA changes the way the brain responds to female hormones, and for babies and children this can mean fertility problems. Such hormones can cause a change in how the brain grows. Long term, this may have something to do with breast, testicular and prostate cancers becoming more common.</p>
<p>And then there is this report: That<a href="http://www.sciencedaily.com/releases/2008/09/080904151629.htm"><strong> BPA might be associated with Metabolic syndrome</strong></a>.</p>
<blockquote><p>&#8220;In a laboratory study, using fresh human fat tissues, the UC team found that BPA suppresses a key hormone, adiponectin, which is responsible for regulating insulin sensitivity in the body and puts people at a substantially higher risk for metabolic syndrome.&#8221;</p></blockquote>
<p>This too makes sense, since there are links between hormones and metabolic syndrome. Metabolic syndrome is a a collection of metabolic problems in how the body handles food. It includes resistance to insulin, and the tendency to put on weight and be diabetic.</p>
<p>So are plastics behind the modern day world wide epidemic of obesity and diabetes too?</p>
<p>A good article that summarizes a lot of the various reports can be found<a href="http://discovermagazine.com/2008/may/18-the-dirty-truth-about-plastic/article_print"><strong> HERE </strong></a>at Discovery magazine.</p>
<p>Regulation of where these plastics are used is the next step. A careful enforcement of laws against companies polluting the waters is also important.</p>
<p>Finally, one has to worry about the huge use of hormones at many levels of society, from birth control pills to hormones given to animals. These chemicals too have been found in the ground water.</p>
<p>On the other hand, one has to make a logical decision about these things.</p>
<p>So should all these suspicious chemicals be banned?</p>
<p>No, because the alternatives have their own problems. But laws banning their use in baby bottles or in toys that kids might put in their mouth would be a good place to start.</p>
<p>The dirty little secret is that getting rid of plastics could cause a lot more problems than it will solve.</p>
<p>But that doesn’t mean people should continue using plastic baby bottles, or giving your kids sodas or juice in cans or plastic bottles.</p>
<p>In the meanwhile,the good news is that public pressure has resulted in <a href="http://www.efluxmedia.com/news_Bisphenol_A_Causes_Health_Issues_in_Primates_23653.html"><strong>Walmart, ToysRUs and other companies</strong></a> from planning to ban the chemical from the products they sell.</p>
<p><em>Nancy Reyes is a retired physician living in the rural Philippines. Her website is Finest Kind Clinic and Fishmarket, and she writes about medicine at HeyDocXanga Blog.</em></p>
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