Health in the future: breast cancer vaccine



Tuesday, 1 June 2010

It’s looking more and more promising as the successful animal-tested breast cancer vaccine moves on to human trials.

Vincent K. Tuohy, PhD, an immunologist and researcher in the department of immunology at the Cleveland Clinic’s Lerner Research Institute, and his team, supported by the National Cancer Institute, have been studying “the possibility of a vaccine that would protect women from breast cancer.”

On May 30, the American researchers published their findings in the online edition of the journal Nature Medicine (to appear in the print version on June 10), showing that a breast cancer vaccine to target women aged 40 and up and those with a high risk of the disease could be just a few years away.

“Most attempts at cancer vaccines have targeted viruses, or cancers that have already developed,” said Joseph Crowe, MD, director of Cleveland Clinic’s Breast Center.

The vaccine works very differently from the two US Food and Drug Administration (FDA) approved vaccines for both cervical- and lung-targeting viruses namely the human papillomavirus (HPV) and Hepatitis B respectively.

It is designed to target ?-lactalbumin, a protein present in most breast cancers and breast milk and should “rev up a woman’s immune system to target ?-lactalbumin – thus stopping tumor formation – without damaging healthy breast tissue,” according to a Lerner Research Institute announcement.

At the end of March, Swedish researchers had also found that “HAMLET” (Human ?-lactalbumin Made LEtal to Tumor cells) kills 40 different types of cancers and explained their findings to a Swedish national radio station, SR- Sveriges Radio.

“Dr. Tuohy is not a breast cancer researcher, he’s an immunologist, so his approach is completely different – attacking the tumor before it can develop. It’s a simple concept, yet one that has not been explored until now,” added Crowe.

Human trials will begin in 2011 and the goal if successful is to vaccinate women over the age of 40 since breast cancer risk increases after 40 and avoid preventative mastectomies.


Remember Рit is not the antigen Рit is the adjuvants; the  preservatives, and heavy metals that are in vaccines that are the problems. After all of the problems with the HPV vaccines, I am not sure that I would opt to be a candidate for this until independent studies have been done on safety and efficacy.


Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.