Universal vaccine in nasal spray

The Sydney Morning Herald

April 30, 2009

AUSTRALIAN scientists have developed a way to make a universal influenza vaccine that can be delivered via nasal spray.

AUSTRALIAN scientists have developed a way to make a universal influenza vaccine that can be delivered via nasal spray.

While not yet ready to be used to counter swine flu, the new approach could provide protection against future pandemics.

An Australian National University immunologist, Mohammed Alsharifi, said yesterday that the current way of making flu vaccines was “not good enough”.

New batches to boost immunity against seasonal flu have to be made each year, because flu viruses mutate so rapidly. It also takes months to develop a new vaccine if a new strain, such as the swine flu, suddenly emerges.

Dr Alsharifi said conventional vaccines also had the disadvantage of stimulating only one of the body’s two immune reactions – the production of antibodies that prevent a specific virus from infecting a cell.

They do not stimulate T-cells, which can fight many different strains of influenza by clearing cells of infection.

“We need a vaccine that induces both types of immune responses, otherwise we will not be able to cope well with new arriving strains of influenza,” he said.

His team’s universal vaccine, based on a human influenza A virus that has been inactivated using gamma radiation, can stimulate both types.

Tests in mice showed that a single dose, given as a nasal spray, protected the rodents against a different flu virus – the deadly strain of bird flu, H5N1.

This type of universal vaccine could buy time until more specific vaccines specific could be developed, said Dr Alsharifi, whose team’s study was published yesterday in the journal PLoS ONE. A nasal spray would also make its easier to distribute in developing countries.

Comment from Leslie –

Not sure if this is scary or not….wonder if this vaccine will have all of the dirty/toxic adjuvants that shots do…So let’s see we shoot mercury and aluminum, borax, MSG and all the garbage that goes into the vaccines right into the brain? HMMMM….

PG

Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.