Vaccine Appears to Have No Impact on Pregnancy Outcome

But recommendation is still to avoid the human papillomavirus vaccine during pregnancy

Modern Medicine

November 24, 2009

There is no evidence that vaccination with the quadrivalent human papillomavirus (HPV) vaccine is harmful to the fetus, but vaccination during pregnancy is still not recommended, according to two studies published in the December issue of Obstetrics & Gynecology.

Suzanne M. Garland, M.D., of the Royal Women’s Hospital in Parkville, Australia, and colleagues combined data from five randomized controlled trials comprising 20,551 women aged 15 to 45 years who received either the quadrivalent HPV vaccine or placebo, and found that among the 1,796 women in the vaccinated group and 1,824 women in the placebo group who became pregnant during the trials, there was no difference between the two groups in terms of pregnancy outcome.

Adrian Dana, M.D., of Merck Research Laboratories in West Point, Pa., and colleagues analyzed post-marketing data on pregnancy outcomes among the 451 live births resulting from 517 reports of pregnancy, and found that among women who were exposed to the quadrivalent HPV vaccine during pregnancy, the prevalence of miscarriages and major birth defects was the same as those in unexposed women.


Comment from Leslie

Really – I thought that I posted an article last week that was stating just the opposite about fetal outcomes and HPV vaccine.

Read this perspective from another source Р from the same study.  No wonder women are so confused about their health care.


Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.