Holy Hormones Journal: I was attending a business women’s network meeting a week or so ago – and I mentioned to the woman sitting next to me that I had just read that 1 in 125 children were being born with congenital heart abnormalities. She turned to me and said; “I wonder what is in the environment that is causing that?”
And that, dear readers is the question of the century. What is it in our environment that is causing autism, Parkinson’s, Alzheimer’s, cancer, – especially breast cancer – and infertility? 1 in 68 kids are on the autism spectrum – that number drops to 1 in 2 boys in NJ – and those stats are from 2012. Are you concerned? 1 in 54 kids are chronically ill – and that chronic illness lasts a life time.
This is not “normal” – yet we are accepting chronic illness and not feeling well as the “new normal.” Although these articles are from 2013, they are just as relevant today – if not more so. Mom’s Across America is fighting the glyphosate issue hand and fist…
They have been in the news lately – because of a rebuttal to a German study that showed the glyphosate was found in breast milk. Researchers at Washington State University – who have ties to Monsanto – found that breast milk was glyphosate free. And who do you believe?
Folks – our environment is toxic. Over 80,000 chemicals have been created – since WWII. Even the chemicals that have been banned because of their toxicity are still in the natural cycle – they have gotten into the soil, have been carried into the waterways – and then are evaporated into the air and cause pollution – and then the rain returns them to the soil.
GreenMedInfo also related the use of Roundup to breast cancer tumors…
An alarming new study, accepted for publication in the journal Food and Chemical Toxicology last month, indicates that glyphosate, the world’s most widely used herbicide due to its widespread use in genetically engineered agriculture, is capable of driving estrogen receptor mediated breast cancer cell proliferation within the infinitesimal parts per trillion concentration range
The study, titled, “Glyphosate induces human breast cancer cells growth via estrogen receptors,” compared the effect of glyphosate on hormone-dependent and hormone-independent breast cancer cell lines, finding that glyphosate stimulates hormone-dependent cancer cell lines in what the study authors describe as “low and environmentally relevant concentrations.”
The results were broken down by the researchers as follows:
- Glyphosate induces T47D, hormone dependent breast cancer cell growth.
- The proliferative effect of glyphosate is mediated via estrogen receptors.
- Glyphosate induces ERE [Estrogen Response Element]-transcription activity via estrogen receptors.
- Glyphosate modulates the expression of E[strogen] R[eceptor] α and E[estrogen] R[eceptor]β in human breast cancer cells.
We are all surrounded with chemicals, they are pass through the umbilical cord – or children’s chronic illness’s and neurological and developmental diseases disorders are indicative of that. We need to detox… this has to be done diligently, religiously and feverishly. Our lives are at stake.
Our man-made environment is killing us. Literally. This is what happens when women’s voices are silenced – not even figured into the equation. And now the damage is done.
Unfortunately, I have more disturbing articles to follow.
Remember the question of the century is not “What is wrong with me?” it is “What have I been exposed to?” and “What am I deficient in?” These two things will help us get back on the path to health and wellness.
Is It Time To Acknowledge Roundup Herbicide As A Contraceptive?
Thursday, July 4th 2013 at 6:00 am
Sayer Ji, Founder
How much longer will we deny the growing body of research linking Roundup to infertility before calling this chemical a contraceptive?
Following closely on the heels of the EPA’s decision to allow Roundup herbicide residues in your food at concentrations a million times higher than shown carcinogenic, a concerning new study published in the journal Free Radical Medicine & Biology implicates the herbicide, and its main ingredient glyphosate, in male infertility, at concentration ranges well within the EPA’s “safe level” for food.
Performed by Brazilian researchers, the study found acute Roundup exposure at low doses (36ppm, 0.036g/L) for 30 minutes induced cell death in Sertoli cells in prepubertal rat testis. Sertoli cells are known as “mother” or “nurse” cells within the testicles, as they are responsible for maintaining the health of sperm cells, and are required for normal male sexual development.
Roundup herbicide exposure was found to induce oxidative stress and to activate multiple-stress response pathways within affected cells, and was associated with an increase in intracellular calcium (Ca2+) concentration leading to Ca2+ overload, and cell death.
Thirty minute incubation tests with glyphosate alone (36 ppm) also increased Ca2+ uptake, and both Roundup and glyphosate were observe to downregulate reduced glutathione levels. As glutathione is an antioxidant (electron donor) found within every cell in the human body, protecting it against oxidative stress, as well as maintaining a wide range of biochemical reactions such as DNA and protein synthesis and repair, amino acid transport, prostaglandin synthesis, amino acid and enzyme activation, a dysregulation of glutathione can result in a wide range of adverse effects.
The researchers noted “Glyphosate has been described as an endocrine disruptor affecting the male reproductive system; however, the molecular basis of its toxicity remains to be clarified. We could propose that Roundup® toxicity, implicating in Ca2+ overload, cell signaling misregulation, stress response of the endoplasmic reticulum and/or depleted antioxidant defenses could contribute to Sertoli cell disruption of spermatogenesis that could impact male fertility.”
This study adds to a growing body of research implicating Roundup herbicide in male infertility:
- A 2007 study published in the journal Reproductive Toxicology found that Roundup herbicide altered the structure of the testis and epididymal region (part of the tubular spermatic duct system), as well as the serum levels of testosterone and estradiol, in male ducks, leading the researchers to conclude that Roundup “…may cause disorder in the morphophysiology of the male genital system of animals.”
- A 2010 male rat study published in the Archives of Toxicology revealed prepubertal exposure to commercial formulation of the herbicide glyphosate alters testosterone levels and testicular morphology, leading researchers to describe the herbicide as “a potent endocrine disruptor.”
- A 2011 male rat study published in the Archives of Toxicology revealed maternal exposure to glyphosate disturbed the masculinization process and promoted behavioral changes and histological and endocrine problems in reproductive parameters.