Dr. Deirdre Little Discusses Findings on Gardasil & Ovarian Failure

In 2012 The British Medical Journal published a stunning paper by an Australian physician who discovered a link between Gardasil and ovarian failure -early menopause in her 16 year old patient. This is very disturbing.  As I have stated before there is danger is vaccinating girls at the most fragile time of their life Рmenarche Рtime of first menstruation РAND vaccinating them without regard to where they are in their menstrual cycle.  It is well established that immunity is at its lowest during the paramenstrum.

Premature ovarian failure 3 years after menarche in a 16-year-old girl following human papillomavirus vaccination
BMJ Case Reports 2012; doi:10.1136/bcr-2012-006879
Deirdre Therese Little, Harvey Rodrick Grenville Ward

Premature ovarian failure in a well adolescent is a rare event. Its occurrence raises important questions about causation, which may signal other systemic concerns. This patient presented with amenorrhoea after identifying a change from her regular cycle to irregular and scant periods following vaccinations against human papillomavirus. She declined the oral contraceptives initially prescribed for amenorrhoea. The diagnostic tasks were to determine the reason for her secondary amenorrhoea and then to investigate for possible causes of the premature ovarian failure identified. Although the cause is unknown in 90% of cases, the remaining chief identifiable causes of this condition were excluded. Premature ovarian failure was then notified as a possible adverse event following this vaccination. The young woman was counselled regarding preservation of bone density, reproductive implications and relevant follow-up. This event could hold potential implications for population health and prompts further inquiry.

Dr. Little speaks frankly about her concerns in this video.


Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.


  1. William Jamison says:

    Dr. Little has extrapolated, from a single case, that this vaccine can cause early menopause in an otherwise healthy young female.

    Dr. Little, aren’t you over-reaching just a bit? Is this how science is done in your eyes?

  2. Cannot speak for Dr. Little. However, there are too many cases reported not to make this link. What happened to observation? Vaccinating girls at the most fragile time of their lives -menarche – is dangerous PERIOD. Too much damage to the neuro-immune-endocrine system. Especially with a challenge/re-challenge. Which is why only 1/3 of girls finish the three vaccine series.

    It is time to bring ‘common sense’ and observation back into science. Especially since science these days is based on studies funded by those who have a vested interest in the outcome.


  3. Well, guess the good doctor was not over-reaching at all.
    Human Papilloma Virus Vaccine and Primary Ovarian Failure: Another Facet of the Autoimmune/Inflammatory Syndrome Induced by Adjuvants.

    In other words – early menopause.
    Looks like a scientific study to me.


  4. I wonder if Mr Jamison realises that Dr Little’s young patient is now unable to have children. I wonder if Mr Jamison understands how devastating this is for her and her family. I wonder if Mr Jamison would be so mean-spirited if she were his daughter or granddaughter. Clearly, Mr Jamison doesn’t recognise that fast-tracking this vaccine without ANY fertility studies is EXACTLY the way science should NEVER be done. In anyone’s eyes.
    Our daughters and now sons are the unwitting test subjects for Gardasil.

  5. Bravo.
    Thank you.


  6. EmailCollector says:

    Leslie: Jamison’s comments don’t have anything to do with whether he realises that the patient can’t have children, or whether he has an understanding of devastation or whether you think he is being “mean-spirited”. Nor should they. His comments shouldn’t change whether it’s his, or someone else’s, daughter. It’s about logical examination of the facts. Because a topic is upsetting doesn’t mean that the evidence is more or less compelling. Lastly, did you read and understand the Am. J. Reprod. Immunol. paper that you cited? What I would like to see is the number of cases of POF as they vary over time before and after vaccine introduction. I’d also like to see the proportion of POF cases that have and have not been vaccinated. We can draw all sorts of conclusions if we only study cases that have POF. For example, 100% of individuals exhibiting POF also had water administered to them every day before POF onset. Does this indicate causation between drinking water and POF? Of course not.

  7. Would you like to contact the author of the paper to have your questions answered?
    If so, please email me at leslie@holyhormones.com

    Hormonally yours,


  8. EmailCollector says:

    No thanks. I can contact the authors myself if needs be… but I don’t need to, because I doubt the data exists. If it does, then the paper should be retracted. I don’t think it should have been allowed to be published to begin with.

  9. What a crack up you are, EmailCollector. Research would indeed be difficult whilst breathing sand.

  10. Johana L. says:

    I experienced the same thing , I received the vaccine my freshman year of high school. After that I started having problems with my menstrul cycle. About a year or so I was diagnosed with POF! Its so sad that my doctors are not doing anything to help me. I feel helpless I cant do anything to help myself.

  11. Johanna – I am so very sorry to hear about your experience post-Gardasil. Your doctors do not know what to do to help you. How old are you now? Did you listen to my interview last week with Dr. Margarita Ochoa-Maya? She is a wonderful endocrinologist. Her web site is http://advancedhealthnh.com

    Dr. Ochoa-Maya might have some thoughts on your situation. How is your health otherwise?
    Did you report the incident to VAERS?

    Are you familiar with the Gardasil/Cervarix survey Chandler Marrs PhD is doing on her blog Hormones Matter? The link is here: http://www.hormonesmatter.com/take-a-health-survey/

    This is the first independent survey of Gardasil injured and non-injured. We are hoping to use the data to get help for the injured and to get the vaccine off the market. We have had over 400 respondents and need 1,000. Please take the time to let us know you experience with the vaccine.

    Thanking your for posting here. If you are on Facebook or Twitter – there are many groups of girls and parents affected by this tragedy.

    Hormonally yours,


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