Effect of the Menstrual Cycle and Hormonal Contraceptives on Human Papillomavirus Detection in Young, Unscreened Women

American College of Obstetrics and Gynecology

July 2010

Channa E. Schmeink, MD, Leon F. Massuger, MD, PhD, Charlotte H. Lenselink, MD, PhD, Wim G. Quint, PhD, Willem J. Melchers, PhD, and Ruud L. Bekkers, MD, PhD

OBJECTIVE: To estimate the effect of the menstrual cycle
and oral contraceptive pill (OCP) use on the prevalence,
incidence, and persistence of human papillomavirus

CONCLUSION: High-risk HPV detection was significantly
influenced by sample timing in the menstrual cycle when analyzed separately for OCP users and women with a natural menstrual cycle. This may have implications in the future, when high-risk HPV detection may
become a primary screening tool in cervical cancer prevention.
(Obstet Gynecol 2010;116:67–75)


My colleague Cynthia Janak and I presented research and date to the FDA about the potential dangers of the HPV vaccine due to the menstrual cycle in March of this year.  This study backs up our concerns…and our research.  In our humble opinion we have proven why this vaccine is dangerous to this age group of women.


Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.