Indications added for Gardasil, breast implants questioned

ACP Internist
American College of Physicians
April 2011



An additional indication of the human papillomavirus vaccine Gardasil for the prevention of anal cancer and associated precancerous lesions due to HPV types 6, 11, 16, and 18 in people ages 9 through 26 years. The vaccine was studied in a randomized, controlled trial of men who self-identified as having sex with men in which it was shown to be 78% effective in the prevention of HPV 16- and 18-related anal intraepithelial neoplasia.

The first mobile radiology application for viewing medical images on the iPhone and iPad. The application allows physicians to view images and make medical diagnoses based on computed tomography, magnetic resonance imaging, and nuclear medicine technology, such as positron emission tomography. It is not intended to replace full workstations and is indicated for use only when there is no access to a workstation.


An FDA review has found a possible association between saline and silicone gel-filled breast implants and anaplastic large-cell lymphoma (ALCL).

Data reviewed by the FDA suggest that patients with breast implants may have a very small but significant risk of ALCL in the scar capsule adjacent to the implant. In total, the agency is aware of about 60 cases of ALCL in women with breast implants worldwide.

Most cases reviewed by the FDA were diagnosed when patients sought medical treatment for implant-related symptoms such as pain, lumps, swelling, or asymmetry that developed after their initial surgical sites were fully healed. These symptoms were due to collection of fluid (peri-implant seroma), hardening of breast area around the implant (capsular contracture), or masses surrounding the breast implant.

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Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.