Estrogen Mimics’ Angry Implications & Autism Questions

Opposing Views

Opinion by Val
August 27, 2010
Health / Autism

Effects of estrogen mimics are concerning per – “The Role of Environmental Factors on the Timing and Progression of Puberty“;  the workshop was initiated due to the need for more study with regard to the effects of estrogen mimics that we are all exposed to in daily living. The workshop consensus is that there is an identifiable trend of earlier puberty onset.

The majority of the panelists concluded that the girls’ data are sufficient to suggest a secular trend toward earlier breast development onset and menarche from 1940 to 1994 but that the boys’ data are insufficient to suggest a trend during this same period. The weight-of-the-evidence evaluation of human and animal studies suggest that endocrine-disrupting chemicals, particularly the estrogen mimics and antiandrogens, and body fat are important factors associated in altered puberty timing. A change in the timing of puberty markers was considered adverse from a public health perspective. The panel recommended research areas to further our understanding of the relationships among environmental factors, puberty-timing outcomes, and other reproductive and adult disease at the individual and population levels.

It seems reasonable to at the very least hypothesize that the estrogen mimics’ effect on girls would be more identifiable than on boys. Concern with regard our modern food chain, the genetic modifications that have transpired – and the possible health affects that might arise have piqued a lot of interest.

A discovery that commonly used food additives are estrogenic has led scientists to suspect that many ingredients added to the food supply may be capable of altering hormones. One expert states that “We’re dealing with this chemical mixture, a cocktail effect, and I would say that if you look at a single compound then you might underestimate the exposure to these environmental estrogens”. This was with regard to research that indicated people are exposed to more environmental endocrine disruptors than what was previously thought. (link)

University of Wisconsin – Madison is in the process of evaluating the effects of endocrine-disrupting chemicals that mimic estrogen, the primary female sex hormone. These chemicals act like estrogen, bind to the estrogen receptors in normal cells, and trigger some — but not necessarily all — of the functions in cells that true estrogen initiates.

Estrogen effects are complex.

Endocrinology…Brain Implications

In one review on brain chemistry of reproductive hormones, in women the following estrogen effects were described:

  • an increase in brain norepinephrine levels
  • a decrease in dopamine release
  • multiple effects on serotonin, and even an effect on blood tryptophan levels (the amino acid from which serotonin is made)
  • protective effects on acetycholine systems (possibly thereby protecting against Alzheimer’s disease)
  • effects on the production of neurotrophic factors, the brain’s own cell fertilizers, now known to be very directly involved in the mechanism of depression
  • an increase in endorphin levels in the brain as well as the bloodstream
  • a possible relationship with melatonin, the sleep-regulating hormone (complex relationship, different in different animal species)
  • promotion of the production of allopregnanolone, a “neurosteroid” with strong antianxiety effects
  • a complex relationship, but clearly affecting the levels of DHEA, another neurosteroid with mood effects.

The moral of the story: there is no simple way to explain… (how estrogen affects mood)

Closing Statement: Is there any question that many health complaints, and even autism can be implicated with regard to estrogen mimics huge presence in the environment?

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Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.