Hormone Balance – Hormone Imbalance- How it affects the immune system


Blending Science with Nature

Fast Facts

  • An imbalance in thyroid and adrenal hormones, testosterone, the estrogen’s (estrone, estradiol, estriol), and progesterone can affect the immune system.
  • Our chemical environment (xenoestrogens) and nutrition are both contributing factors to hormone imbalance.
“A hormone is a chemical substance which is produced in one location of the body and travels to another to convey, create, or generate a response”.
Dr. Jesse Stoff (M.D.).

It’s also important to note that no hormone works in isolation from other hormones; they all function within a complex, subtle web of interconnectedness. Reference: Dr. John Lee Many hormones have an effect on the immune system, disease and each other.
Thyroid Hormone Imbalance and the Immune System
“Thyroid hormone stimulates the activity of Natural Killer (NK) cells [cells in the immune system].” Dr. Jesse Stoff

What nutritional element does the thyroid need to function? Iodine.
Janice Wittenberg, RN states that “Iodine in particular is important to the production of the thyroid hormone. Low to sub-clinical [not measurable through testing] thyroid function is very common.  Soils in the mid-west and areas along the St. Lawrence have the lowest iodine concentrations and largest number of thyroid related problems in the world.”

“Estrogen inhibits thyroid hormone activity and thus exacerbates thyroid deficiency. In contrast, progesterone, cortisol, and testosterone are thyroid allies.” Dr. John Lee

The most common symptoms (there are many) of a low functioning thyroid are fatigue and intolerance to cold according to Dr. James Balch.

Adrenal Glands and the Immune System
Janice Wittenberg  R.N. in her book, “The Rebellious Body”, comments on adrenal glands by saying that they can, as a result of stress and nutritional deficiencies, produce hormones that inhibit the production of prostaglandins that interfere with immune response.


Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.