2001 Study: Circadian Rhythm CHAOS as Biomarker for Breast Cancer

Leslie Carol Botha: Serious? A 2001 study on circadian rhythm chaos as a bio marker and what has been done in the last 13 years? Not a damn thing. No education, no awareness. In fact, what we have seen in an explosion of circadian and endocrine system disruptors with synthetic hormones and the push to get rid of menstruation all together with pills, injections, implants, rings and IUD’s.¬† And that does not even take into account the estrogen mimickers in the environment.¬† Oh, yeah one year later is 2002 was the shocker when WHI stopped the first independent study on HRT because the risks outweighed the benefits.

And now look at all the lawsuits women have filed against the Pharma companies because HRT use – circadian disruption/ CHAS has cause their breast cancer.


Circadian rhythm chaos: a new breast cancer marker.

Int J Fertil Womens Med. 2001 Sep-Oct;46(5):238-47.

Circadian rhythm chaos: a new breast cancer marker.


Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois, USA.


The most disappointing aspect of breast cancer treatment as a public health issue has been the failure of screening to improve mortality figures. Since treatment of late-stage cancer has indeed advanced, mortality can only be decreased by improving the rate of early diagnosis. From the mid-1950s to the mid-1970s, it was expected that thermography would hold the key to breast cancer detection, as surface temperature increases overlying malignant tumors had been demonstrated by thermographic imaging. Unfortunately, detection of the 1-3 degrees C thermal differences failed to bear out its promise in early identification of cancer. In the intervening two-and-a-half decades, three new factors have emerged: it is now apparent that breast cancer has a lengthy genesis; a long-established tumor-even one of a certain minimum size-induces increased arterial/capillary vascularity in its vicinity; and thermal variations that characterize tissue metabolism are circadian (“about 24 hours”) in periodicity. This paper reviews the evidence for a connection between disturbances of circadian rhythms and breast cancer. Furthermore, a scheme is proposed in which circadian rhythm “chaos” is taken as a signal of high risk for breast cancer even in the absence of mammographic evidence of neoplasm or a palpable tumor. Recent studies along this line suggest that an abnormal thermal sign, in the light of our present knowledge of breast cancer, is ten times as important an indication as is family history data.

Source: Our friendly government Pubmed.gov


Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.