Allergies during menopause – can progesterone help relieve them ?

February 7, 2011

Every woman will have her period stop along with ovulation and this period is called menopause, but one of the problems that arise from this situation is allergic reaction. Menopause comes in the period from 45 to 55, approximately 50 years of age, but this can happen even before 40. This situation occurs among 1% of female population and it is called premature ovarian failure or premature menopause. It can lead to many problems and one of them is allergic reaction. This happens mostly due to the compromised immune system, which makes women prone to attacks from allergens in the environment. Allergens can be inhaled or eaten and they will provoke allergic reaction. There are a lot of these allergens in the nature, but their effects on a human vary from one person to another due to specific sensitivity of an individual. Humans can be allergic to every single item present in the world.

Progesterone is the main reason why allergic reactions during menopause occur. Treatment is very difficult, but this is a problem that happens rarely. Every person can develop allergic reaction in a different way but the severity depends on several factors such as immune system’s response, exposure level and a type of the allergen.


Allergic reactions during menopause are created by progesterone, both natural and synthetic. It will cause problems such as hives (or urticaria) or a rash, but it can lead to serious problems such as anaphylactic shock, which can be deadly. Allergic rash caused by natural occurring progesterone can be very problematic for the treatment.


Abnormal reactivity of the progesterone can lead to the episodes of anaphylaxis, which cannot be explained by anyone, but which can occur at any time. The cause of this problem has been seen in the histamine release from the basophile, which makes cells prone to the mast cell degranulators. Also, the cause of this problem has been detected in the progesterone and estrogen hormones, according to the scientists from the Austin in Texas. IgE antibodies in the body decrease during the menopause period. It is important to say that these allergies can occur at any time and you can be prone to them on one day, while tomorrow you do not have to be prone to them at all. Scientists from all around the world are trying to find a solution for this increasing problem in the world.


Jury is out on this article…although I intrigued with the reference to IgE and histamine.


Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.