Premenstrual Syndrome and St. John’s Wort


August 17, 2010

St. John’s Wort (Hypericum perforatum) shows promise in aiding those suffering from premenstrual syndrome.  In a recent study from the University of Leeds researchers found that St John’s Wort was “statistically superior to placebo in improving physical and behavioral symptoms of PMS (p<0.05).”  Other outcomes of the study including hormonal assessments, anxiety, depression, and other variables did not improve significantly.  Another study of PMS-like symptoms among perimenopausal women found significant reduction in anxiety and hydration along with other outcomes using a combination of St. John’s Wort and chaste tree/berry (Vitex agnus-castus).  These additional studies from the last year will help pave the way for future research to isolate issues like dose, clinical prediction variables and underlying mechanisms for action.

Note:  These mini-reviews are designed as updates and direct the reader to the full text of current research.  The abstracts presented here are no substitute for reading and critically reviewing the full text of the original research.  Where permitted we will direct the reader to that full text.



Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.