February 20, 2010
A sex hormone can help in treatment of serious brain injuries. Researchers at 17 US medical centres are planning to start the experiment on trial basis, according to a presentation at an annual US gathering of scientists. Progesterone, a steroid hormone which is engaged in the female menstrual cycle and pregnancy, can reduce the death rate from traumatic brain injury by half.
The National Institutes of Health through Emory University in Atlanta, Georgia, announced at the annual gathering of the American Association for the Advancement of Science in San Diego, that it will fund the final phase of the clinical trials, which is expected to begin in March. About 1,140 brain damaged patients will be enrolled over three to six years. David Wright will lead the clinical trial.
“No new treatment for severe TBI has been approved in over 30 years. With such promising success in laboratory testing and in our previous clinical trial, we hope to conclude in this national trial that progesterone – along with standard medical trauma care – works better than standard medical care alone in reducing brain damage caused from a TBI”, said Dr. David Wright.
This disease is common in US. Approximately, two million adults and children in the US undergo TBI, each year.