Study: Gender Differences in Bipolar I Patients

Holy Hormones Journal:  If hormones are the messengers…. then bipolar is a result in a breakdown in the messages. Is it really a surprise that one sex may react one way – and the other another way. No wonder we are struggling with our relationships. Women blame men for being so manic – and drinking and other compulsive behaviors – and men rage at their partners for their constant weeping.

bipolar disorder2Guess what – it is not your husband who is manic – nor is it your wife who is wailing uncontrollably.  It is your neuro-chemical makeup. We are no longer the ‘Id’ or ‘ego’ – our personality is 100% dependent on the communication systems in the frontal lobe of our brain. When the communicati9on is off – the personality is off.

Does your husband want to be manic?  Does your wife want to be reduced to tears at a moment’s notice? No. We have become locked in the rabbit holes of our minds – without even knowing it…. and we do not know how to get out.  How many of us apologize to each other after another night of arguing… and how many of us doing it again, and again, and again – until the relationship is totally worn out – and we end up in divorce court.

It would also be interesting to have more details from a study as to where a woman is in her menstrual cycle – or what phases of the moon the outbreaks took place.  I mean it is already well known that emergency rooms and jails fill up at the full moon.  But then again, that is a woman’s and a natural cycle researcher’s perspective to get some clarity and understanding – instead of accepting and diagnosing.

I have said this time and again, women are naturally bipolar due to hormone shifts in the menstrual cycle… depends on how high the rise in hormones and how deep the fall on the other side of ovulation.  How about men and that ‘manstrual cycles’?  Where are their highs and lows.

According to Statistic Brain  approximately 5.7 million adults have been diagnosed with bipolar disorder. My concern is for young women who have been diagnosed with this disorder.  Of course, most of you are now aware I am aligned with a company out of Canada, called ‘Truehope’.  They have developed a broad-spectrum micronutrient that is highly bio available and have now gotten over 100,000 people off their medications.  Anthony Stephan’s story in developing this product was the subject of my radio interview last week.

Just remember this quote from Stephan….

“When they open the history book ten years from now, it will talk about how mental illness
was found to be nothing more than a nutrient deficiency disorder.” ~ Anthony Stephan

Maybe we should all be looking at nutrition before we run that relationship right into the ground.

Other Bipolar Statistics

Total percent of people that suffer from Bi-Polar disorder 5%
Average Age of Bipolar Onset 25 years old
Percent child will get Bi-Polar when 1 parent has it 23%
Percent child will get Bi-Polar when both parents are diagnosed 66%
Average Reduced Life span from Bi-Polar 9.2
Percent of diagnosed Bi-Polar who commit suicide 20%
Percent of people who receive correct diagnosis within 3 years 25%
Percent of people with Bi-Polar who are Obese 35%
Percentage of curing Bi-Polar with Lithium 77%
Percent of people with Bi-Polar who will receive 1 misdiagnosis 70%


Journal of Affective Disorders Study


Bipolar illness in women was characterised by the predominance of depression, as indicated by a depressive polarity at onset, higher rates of mixed mania, more suicidal behaviour, and a greater number of temperaments with depressive propensities. In contrast, the manic component was found to predominate in men. Men also had an earlier onset of their illness. Women displayed more comorbidities with eating, anxiety, and endocrine/metabolic disorders, whereas men were more comorbid with alcoholism and other forms of substance abuse, neurological, and cancer disorders. The following independent variables were associated with male gender: being single (+), depressive temperament (-), excessive alcohol use (+), cyclothymic temperament (-), excessive other substance use (+), mood congruent psychotic features (+), and manic polarity at onset (+).


Findings from this study tend to confirm most of the differences previously observed among bipolar men and women. Furthermore, these results draw attention to the risks that may be specifically linked to gender differences in bipolar I patients.

Manic Men, Weeping Women? Bipolar Disorder Hits Sexes Differently, Study Shows

September 16, 2013

Bipolar disorder may strike differently depending on sex. A new study shows men with the mood disorder tend to have more manic phases, while Bipolar-Disorder-testbipolar women fall more on the depressive side.

The research—published in the Journal of Affective Disorders—involved more than 1,000 men and women diagnosed with bipolar I disorder. Bipolar I is a mood disorder featuring manic episodes that alternate with periods of hypomania (extreme elation) and/or major depression.

The study found depressive symptoms were more dominant in bipolar women, while manic symptoms were more dominant in men. Researchers say this can explain some of the differences in outcomes for bipolar men and women, such as the fact that women tend to go longer before receiving a correct diagnosis.

Women tend to seek treatment for the first time during a depressive phase, leading to depression diagnoses rather than bipolar disorder. Bipolar women also have higher suicide attempt rates than men, another fact that could be explained by their greater tendency toward depression.

Read full article…


Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.