How Hormones Help Store or Burn Body Fat – Guest Post by Jonathan Bailor

I interviewed Jonathan Bailor, author of The Smarter Silence of Slim on my radio show on June 4. The show was fascinating.  Bailor’s well-received research indicates that weight loss is not due solely to exercise and calories – but shedding unwanted pounds is more importantly about a balanced and well functioning hormone communication system.  Jonathan has agreed to be a guest blogger on my site. He will writing articles to educate all of us about hormone interaction with weight loss.  Thank you Jonathan for your brilliant research and work. The Smarter Science of Slim can be found on Wonderful, easy to read book for everyone who is wondering why they cannot lose weight.

By Jonathan Bailor
June 22, 2012

Jonathan Bailor has a proven track record and a passion for solving tough problems. He is an accomplished public speaker with a knack for entertaining while he educates. Bailor speaks to and consults with Fortune 50 companies and has done so for the past decade. As an entrepreneur, Bailor has started successful businesses, authored the critically acclaimed book “The Smarter Science of Slim,” produced a promotional magazine, helped develop a radio show, holds more than 20 U.S. Patents and invented the marque feature in Microsoft Office 2010.

The critical effect hormones have on body fat has been well known in scientific circles for a long time. Especially the hormone insulin. Most of us know insulin only in reference to diabetics. They need insulin shots. Yet a true understanding of how hormones generally—and insulin specifically—work in relation to body fat reveals the cause of, and solution to, weight gain and related diseases such as diabetes.[i]

Researcher P.J. Havel from the University of California presents the scientific explanation of how hormones handle our love handles: “Short-term [hormonal] signals are primarily from the GI tract [digestive system]…and are involved in promoting sensations of satiety…. The long-term [hormonal] signals insulin and leptin are produced and circulate in proportion to recent energy intake and body adiposity [body fat]. Together, the short- and long-term [hormonal] signals interact to regulate energy balance…” In other words, our digestive system, muscle tissue, and fat tissue are constantly communicating with our nervous system and brain via hormones. They are talking about how much fuel they think we need to keep us at our set-point. If they think we are at risk of rising above our set-point, they automatically decrease our calories in and increase our calories out, and vice versa.[ii]



When we eat SANE high-quality calories, this conversation goes well. The right amount of hormones are used and the right message gets across: “Burn body fat.” When our hormones are able to do their job, we have the ability to burn body fat, and away our body fat goes.

However, when we eat inSANE low-quality calories, communication breaks down. Our metabolism doesn’t have a good idea of how much fuel we need, hormones go bonkers, and our metabolism demands more food since it does not know what is going on and errs on the side of not starving. Thanks to this communication breakdown, we end up overeating, hormonally clogged, and heavier.[iii]

The good news is that we can control this conversation. The even better news is that we do so most effectively by eating more and exercising less—but smarter. I know this sounds a bit counterintuitive, but the largest scientific analysis of wellness ever conducted backs this up.

If we keep doing what we’ve always done, we will keep getting what we’ve always gotten. It’s time to eat smarter, exercise smarter, and live better by using the most robust scientific research in the world to control the hormonal conversation taking place within us.

–          Jonathan Bailor,

[i] A sampling of supporting research:

–           Woods SC, Figlewicz Lattemann DP, Schwartz MW, Porte D Jr. A re-assessment of the regulation of adiposity and appetite by the brain insulin system. Int J Obes.1990;14 Suppl 3:69-73; discussion 74-6. Review. PubMed PMID: 2086517.

–           Porte D Jr, Woods SC. Regulation of food intake and body weight in insulin. Diabetologia. 1981 Mar;20 Suppl:274-80. PubMed PMID: 7014326.

–           Woods SC, Benoit SC, Clegg DJ, Seeley RJ. Clinical endocrinology and metabolism. Regulation of energy homeostasis by peripheral signals. Best Pract Res Clin Endocrinol Metab. 2004 Dec;18(4):497-515. Review. PubMed PMID: 15533772.

[ii] A sampling of supporting research:

–           Havel PJ. Peripheral signals conveying metabolic information to the brain: short-term and long-term regulation of food intake and energy homeostasis. Exp Biol Med (Maywood). 2001 Dec;226(11):963-77. Review. PubMed PMID: 11743131.

–           Havel PJ. Dietary fructose: implications for dysregulation of energy homeostasis and lipid/carbohydrate metabolism. Nutr Rev. 2005 May;63(5):133-57.Review. PubMed PMID: 15971409.

–           Murphy KG, Dhillo WS, Bloom SR. Gut peptides in the regulation of food intake and energy homeostasis. Endocr Rev. 2006 Dec;27(7):719-27. Epub 2006 Oct 31. Review. PubMed PMID: 17077190.

–           Hameed S, Dhillo WS, Bloom SR. Gut hormones and appetite control. Oral Dis. 2009 Jan;15(1):18-26. Epub 2008 Oct 17. Review. PubMed PMID: 18939959.

[iii] A sampling of supporting research:

–           Papoushek C. The “glitazones”: rosiglitazone and pioglitazone. J Obstet Gynaecol Can. 2003 Oct;25(10):853-7. Review. Erratum in: J Obstet Gynaecol Can. 2003 Nov;25(11):907. PubMed PMID: 14532954.

–           Sinha A, Formica C, Tsalamandris C, Panagiotopoulos S, Hendrich E, DeLuise M, Seeman E, Jerums G. Effects of insulin on body composition in patients with insulin-dependent and non-insulin-dependent diabetes. Diabet Med. 1996 Jan;13(1):40-6. PubMed PMID: 8741811.

–           Laville M, Andreelli F. [Mechanisms for weight gain during blood glucose normalization]. Diabetes Metab. 2000 Jun;26 Suppl 3:42-5. Review. French. PubMed PMID: 10945152.

–           Carlson MG & Campbell PJ. Intensive insulin therapy and weight gain in IDDM. Diabetes 1993 42 1700–1707.

–           Joslin, Elliott Proctor, C. Ronald. Kahn, and Gordon C. Weir. Joslin’s Diabetes Mellitus. Philadelphia: Lea & Febiger, 1994. Print.

–           MacKay, Eaton M., Callaway, James W., Barnes, Richard H. Hyperalimentation in Normal Animals Produced by Protamine Insulin: Three Figures J. Nutr. 1940 20: 59-66

–           Hoebel BG, Teitepoundaum P. Weight regulation in normal and hypothalamic hyperphagic rats. J Comp Physiol Psychol. 1966 Apr;61(2):189-93. PubMed PMID: 5909295.

–           Havel PJ. Update on adipocyte hormones: regulation of energy balance and carbohydrate/lipid metabolism. Diabetes. 2004 Feb;53 Suppl 1:S143-51. Review. PubMed PMID: 14749280.

–           Rosenbaum M, Vandenborne K, Goldsmith R, Simoneau JA, Heymsfield S, Joanisse DR, Hirsch J, Murphy E, Matthews D, Segal KR, Leibel RL. Effects of experimental weight perturbation on skeletal muscle work efficiency in human subjects. Am J Physiol Regul Integr Comp Physiol. 2003 Jul;285(1):R183-92. Epub 2003 Feb 27. PubMed PMID: 12609816.


Author: Leslie Carol Botha

Author, publisher, radio talk show host and internationally recognized expert on women's hormone cycles. Social/political activist on Gardasil the HPV vaccine for adolescent girls. Co-author of "Understanding Your Mood, Mind and Hormone Cycle." Honorary advisory board member for the Foundation for the Study of Cycles and member of the Society for Menstrual Cycle Research.