Holy Hormones Journal: Diabetes used to be blamed solely on an individual’s diet and lifestyle. What cannot be denied is that T2DM has now reached epidemic proportions with a worldwide prevalence of 415 million – anticipated to reach 615 million by 2040. However, it appears there is a deeper connection to diabetes and that is the breakdown in circadian rhythms in the body. The hormonal rhythmic connection that drives the chemical messengers to every cell in the body.
What are circadian rhythms? They are the magical mechanisms of actions that plants, animals, and humans innately follow to adapt their biological rhythms to synchronize with the Earth’s revolutions.
We are going to hear more about circadian medicine in the coming years – and will be marked as the biggest breakthrough in the medical field in decades. In fact, in 2017, three scientists received the Nobel Prize in Physiology or Medicine “for their discoveries of the molecular mechanisms that control circadian rhythms.”
Moon cycles aren’t just for astrologists and crystal-wielding spiritualists. All organisms operate on a 24-hour circuit that governs critical functions such as blood pressure, heart rate, body temperature, hormone levels, metabolism, sleep, and even behavior—all in time with shifts between day and night. ~Wired
An emerging connection between circadian rhythm disruption and type 2 diabetes mellitus
“…environmental factors such as caloric intake and physical inactivity have long been appreciated to augment susceptibility to T2DM. More recently, however, circadian rhythm disruption has been gaining greater appreciation as an emerging environmental risk factor for T2DM.”
“Circadian disruption is defined as “misalignment between the endogenous circadian system and behavioral circadian cycles” (for example, sleep-wake and fasting-feeding). In today’s 24-hour society, circadian disruption is becoming increasingly commonplace — driven primarily by increased exposure to artificial lighting, rotational and night shift work, social jet lag as well as comorbidities such as obesity and sleep disorders. For example, in the United States alone, more than 70 percent of adults report inadequate sleep quality and duration and nearly 20 million people are exposed to daily shift work-like conditions.
“…Multiple strands of evidence support the causative relationship between circadian disruption and impaired glucose homeostasis. First, individuals engaged in work conditions characterized by circadian disruption, such as rotational shift and night work, exhibit higher prevalence of diabetes, impaired glucose tolerance and metabolic syndrome.”